지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 3 - 9 (7page)
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초록· 키워드
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Background: Hemoglobin A1c (HbA1c) level is an indicator of the average blood glucose concentration of the past 2 to 3 months. Studies on the association of HbA1c levels with cardiovascular disease have reported inconsistent findings groups stratified by gender, age, and race. Therefore we conducted this study to determine the relationship between HbA1c levels and metabolic syndrome in a Korean population participating in medical check-up programs.
Methods: The study population comprised 7,301 nondiabetic Korean subjects (3,384 men and 3,917 women) who had enrolled for a medical check-up program. All subjects were divided into 5 groups on the basis of their HbA1c levels. Age, blood pressure, abdominal obesity, fasting glucose levels, lipid profile and high sensitivity C-reactive protein (hsCRP) levels were compared among the groups. In addition, we also investigated the association of HbA1c levels with cardiovascular risk factors and metabolic syndrome.
Results: Age, waist circumference, body mass index, blood pressure, hsCRP levels, lipid profile and fasting glucose levels differed significantly among the 5 HbA1c groups, both in men and women. The possibility of the occurrence of metabolic syndrome increased as HbA1c levels increased,both in men and women. Abdominal obesity was the most common component of metabolic syndrome and more prominently occurred in women.
Conclusions: HbA1c levels were significantly correlated to metabolic syndrome among these Korean subjects and abdominal obesity was the most frequently observed component of metabolic syndrome. Thus, abdominal obesity should be treated when high HbA1c levels are detected,particularly in women, even though the patient is not diabetic
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참고문헌 (21)
참고문헌 신청
American Diabetes Association / 2010 / Diagnosis and classification of diabetes mellitus / Diabetes Care 33 : 62 ~ 69
Bakker SJ / 1998 / Association between HbA1c and HDLcholesterol independent of fasting triglycerides in a Caucasian population: evidence for enhanced cholesterol ester trans
Balkau B / 1998 / High blood glucose concentration is a risk factor for mortality in middle-aged nondiabetic men. 20-year follow-up in the Whitehall Study, the Paris Prospect
Bjornholt JV / 1999 / Fasting blood glucose: an underestimated risk factor for cardiovascular death. Results from a 22-year follow-up of healthy nondiabetic men / Diabetes Ca
DeFronzo RA / 1991 / Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease / Diab
Bakker SJ / 1998 / Association between HbA1c and HDLcholesterol independent of fasting triglycerides in a Caucasian population: evidence for enhanced cholesterol ester trans
Balkau B / 1998 / High blood glucose concentration is a risk factor for mortality in middle-aged nondiabetic men. 20-year follow-up in the Whitehall Study, the Paris Prospect
Bjornholt JV / 1999 / Fasting blood glucose: an underestimated risk factor for cardiovascular death. Results from a 22-year follow-up of healthy nondiabetic men / Diabetes Ca
DeFronzo RA / 1991 / Insulin resistance. A multifaceted syndrome responsible for NIDDM, obesity, hypertension, dyslipidemia, and atherosclerotic cardiovascular disease / Diab
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