지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 256 - 262 (7page)
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Objective To compare the rate of progression of de novo lesion between the cardiac rehabilitation (CR) and control groups.Methods This is a retrospective observational study. Patients who received drug-eluting stent (DES) due to acute coronary syndrome were included as subjects. The CR group received eight weeks of early CR program, and sustained a self-exercise program in the homes. The control group was instructed to exercise independently. Nine months after the first insertion of DES, we implemented follow-up coronary angiography, and compared the rate of progression of de novo lesion by quantitative angiographic measurement between the two groups. Results A total of 81 patients were recruited as subjects to CR group (n=32) or control group (n=49). At nine months, late luminal loss was 0.04±0.23 mm in the CR group and 0.00±0.31 mm in the control group (p=0.54, observed power=0.10). Late loss was -0.90%±9.53% in the CR group and 0.80%±11.15% in the control group (p=0.58, observed power=0.05). No target lesion revascularization procedures were needed in the CR group, while two in the control group (p=0.25). In the CR group, mean VO2max was significantly improved from 24.36±5.00 to 27.68±5.24 mL/kg/min (p<0.001).Conclusion We could not observe a statistically significant difference in the progression rate of de novo lesion between the CR and control groups. Thus the current amount of nine months exercise-based CR program does not seem to have a distinct impact on the retardation of de novo coronary lesion in patients who received percutaneous coronary intervention with DES.
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참고문헌 (25)
참고문헌 신청
Post MJ / 1997 / Arterial remodeling after balloon angioplasty or stenting in an atherosclerotic experimental model / Circulation 96:996~1003
Wentzel JJ / 2001 / Relationship between neointimal thickness and shear stress after Wallstent implantation in human coronary arteries / Circulation 103:1740~1745
Saleh N / 2007 / Serum C-reactive protein response to percutaneous coronary intervention in patients with unstable or stable angina pectoris is associated with the risk of clinical restenosis / Atherosclerosis 195:374~378
Munk PS / 2009 / High-intensity interval training may reduce in-stent restenosis following percutaneous coronary intervention with stent implantation: a randomized controlled trial evaluating the relationship to endothelial function and inflammation / Am Heart J 158:734~741
Schuler G / 1992 / Regular physical exercise and low-fat diet: effects on progression of coronary artery disease / Circulation 86:1~11
Wentzel JJ / 2001 / Relationship between neointimal thickness and shear stress after Wallstent implantation in human coronary arteries / Circulation 103:1740~1745
Saleh N / 2007 / Serum C-reactive protein response to percutaneous coronary intervention in patients with unstable or stable angina pectoris is associated with the risk of clinical restenosis / Atherosclerosis 195:374~378
Munk PS / 2009 / High-intensity interval training may reduce in-stent restenosis following percutaneous coronary intervention with stent implantation: a randomized controlled trial evaluating the relationship to endothelial function and inflammation / Am Heart J 158:734~741
Schuler G / 1992 / Regular physical exercise and low-fat diet: effects on progression of coronary artery disease / Circulation 86:1~11
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