지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제15권 제2호
- 발행연도
- 2017.1
- 수록면
- 177 - 180 (4page)
이용수
초록· 키워드
오류제보하기
Objective: Although aripiprazole has been widely used to treat various psychiatric disorders, little is known about the adequate dosage for Asian patients in clinical practice. Hence, we evaluated the initial and maximum doses of aripiprazole from 2004 to 2014 to estimate the appropriate dosage for Korean psychiatric inpatients in clinical practice.
Methods: In this retrospective study, we reviewed the medical records of patients who were hospitalized in five university hospitals in Korea from March 2004 to December 2014. The psychiatric diagnosis according to the text revision of the Diagnostic and Statistical Manual of Mental Disorders, 4th edition during index hospitalization and the initial and maximum doses of aripiprazole were evaluated.
Results: There were 74 patients in Wave 1 (2004-2006), 201 patients in Wave 2 (2007-2010), and 353 patients in Wave 3 (2011-2014). The initial doses of aripiprazole in all diagnostic groups were significantly lower in Wave 3 than in Wave 2. The maximum doses of aripiprazole in each diagnostic group were not significantly different among Waves 1, 2, and 3.
Conclusion: The relatively low initial doses of aripiprazole documented in our study may reflect a strategy by clinicians to minimize the side effects associated with aripiprazole use, such as akathisia.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
Basu R / 2006 / Dose-dependent rapid-onset akathisia with aripiprazole in patients with schizoaffective disorder / Neuropsychiatr Dis Treat 2 : 241 ~ 243
Citrome L / 2005 / Dosing of second-generation antipsychotic medication in a state hospital system / J Clin Psychopharmacol 25 : 388 ~ 391
Citrome L / 2009 / Dose trends for second-generation antipsychotic treatment of schizophrenia and bipolar disorder / Schizophr Res 108 : 238 ~ 244
Di Sciascio G / 2015 / Aripiprazole : from pharmacological profile to clinical use / Neuropsychiatr Dis Treat 11 : 2635 ~ 2647
Farmer CA / 2011 / Aripiprazole for the treatment of irritability associated with autism / Expert Opin Pharmacother 12 : 635 ~ 640
Citrome L / 2005 / Dosing of second-generation antipsychotic medication in a state hospital system / J Clin Psychopharmacol 25 : 388 ~ 391
Citrome L / 2009 / Dose trends for second-generation antipsychotic treatment of schizophrenia and bipolar disorder / Schizophr Res 108 : 238 ~ 244
Di Sciascio G / 2015 / Aripiprazole : from pharmacological profile to clinical use / Neuropsychiatr Dis Treat 11 : 2635 ~ 2647
Farmer CA / 2011 / Aripiprazole for the treatment of irritability associated with autism / Expert Opin Pharmacother 12 : 635 ~ 640
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