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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한정신약물학회 Clinical Psychopharmacology and Neuroscience Clinical Psychopharmacology and Neuroscience 제13권 제2호
- 발행연도
- 2015.1
- 수록면
- 129 - 137 (9page)
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초록· 키워드
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Psychiatric disorders in general, and major depression and anxiety disorders in particular, account for a large burden of disability, morbidity and premature mortality worldwide. Omega-3 polyunsaturated fatty acids (PUFAs) have a range of neurobiological activities in modulation of neurotransmitters, anti-inflammation, anti-oxidation and neuroplasticity, which could contribute to psychotropic effects. Here we reviewed recent research on the benefits of omega-3 PUFA supplements in prevention against major depression, bipolar disorders, interferon-α-induced depression patients with chronic hepatitis C viral infection, and posttraumatic stress disorder. The biological mechanisms underlying omega-3 PUFAs’psychotropic effects are proposed and reviewed. Nutrition is a modifiable environmental factor that might be important in prevention medicine, which have been applied for many years in the secondary prevention of heart disease with omega-3 PUFAs. This review extends the notion that nutrition in psychiatry is a modifiable environmental factor and calls for more researches on prospective clinical studies to justify the preventive application of omega-3 PUFAs in daily practice.
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참고문헌 (24)
참고문헌 신청
Bailey RL. / 2013 / Why US adults use dietary supplements / JAMA Intern Med 173 : 355 ~ 361
Collins PY. / 2011 / Grand challenges in global mental health / Nature 475 : 27 ~ 30
Cyril S. / 2013 / Urbanisation, urbanicity, and health : a systematic review of the reliability and validity of urbanicity scales / BMC Public Health 13 : 513 ~
Gomez-Pinilla F. / 2008 / Brain foods : the effects of nutrients on brain function / Nat Rev Neurosci 9 : 568 ~ 578
Han C. / 2013 / Do we need to consider ethno-cultural variation in the use of atypical antipsychotics for Asian patients with major depressive disorder? / CNS Drugs 27 (Suppl
Collins PY. / 2011 / Grand challenges in global mental health / Nature 475 : 27 ~ 30
Cyril S. / 2013 / Urbanisation, urbanicity, and health : a systematic review of the reliability and validity of urbanicity scales / BMC Public Health 13 : 513 ~
Gomez-Pinilla F. / 2008 / Brain foods : the effects of nutrients on brain function / Nat Rev Neurosci 9 : 568 ~ 578
Han C. / 2013 / Do we need to consider ethno-cultural variation in the use of atypical antipsychotics for Asian patients with major depressive disorder? / CNS Drugs 27 (Suppl
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