지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
- 수록면
- 800 - 809 (10page)
이용수
초록· 키워드
오류제보하기
Objective : Although chronic prostatitis/chronic pelvic pain syndrome(CP/CPPS) is a common disease, there is no consensus on the etiology or pathology and treatment. This was a double-blinded, placebo-controlled, randomized clinical trial, investigating the therapeutic effects of the traditional Korean medicine, Bosingunyang-tang(BSGYT).
Method : Participants who met US National Institutes of Health (NIH) consensus criteria for CP/CPPS were entered after applying inclusion/exclusion criteria. They were randomized to the BSGYT or placebo group, and treated three times a day for 6 weeks. NIH-Chronic Prostatitis Symptom Index (NIH-CPSI) was used to estimate the clinical symptoms of CP/CPPS. Prostaglandin E2 and β-endorphin in prostatic fluid, collected by 2-glass pre-massage and post-massage test, were analyzed as factors associated with pain and inflammation.
Result : The mean decrease in NIH-CPSI total score of the BSGYT group was 11.0 points, which is 5.7 points more than the placebo group. (Mann Whitney test P=0.038) Also the BSGYT group showed three times higher response rate than the placebo group in NIH-CPSI pain subscale score. (Fisher's exact test P=0.027) In those responders, prostaglandin E2 decreased significantly. (Wilcoxon's signed-ranks test P=0.037). No specific side effects were observed.
Conclusion : After a 6-week treatment period, BSGYT improved clinical symptoms of CP/CPPS patients by decreasing PGE2 level in prostatic fluid.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Alexander RB / 2004 / Ciprofloxacin or tamsulosin in men with chronic prostatitis/chronic pelvic pain syndrome: a randomized, double-blind trial / Ann Intern Med 141 (8) : 58
Berger RE / 2007 / Pelvic tenderness is not limited to the prostate in chronic prostatitis/chronic pelvic pain syndrome (CPPS) type IIIA and IIIB: comparison of men with and
Capodice JL / 2005 / Complementary and alternative medicine for chronic prostatitis/chronic pelvic pain syndrome / Evid Based Complement Alternat Med 2 (4) : 495 ~ 501
Capodice JL / 2007 / Stone BA, Kapan S, et al. A pilot study on acupuncture for lower urinary tract symptoms related to chronic prostatitis/chronic pelvic pain / Chin Med 2
Collins MM / 1999 / Distinguishing chronic prostatitis and benign prostatic hyperplasia symptoms: results of a national survey of physician visits / Urology 53 (5) : 921 ~ 92
Berger RE / 2007 / Pelvic tenderness is not limited to the prostate in chronic prostatitis/chronic pelvic pain syndrome (CPPS) type IIIA and IIIB: comparison of men with and
Capodice JL / 2005 / Complementary and alternative medicine for chronic prostatitis/chronic pelvic pain syndrome / Evid Based Complement Alternat Med 2 (4) : 495 ~ 501
Capodice JL / 2007 / Stone BA, Kapan S, et al. A pilot study on acupuncture for lower urinary tract symptoms related to chronic prostatitis/chronic pelvic pain / Chin Med 2
Collins MM / 1999 / Distinguishing chronic prostatitis and benign prostatic hyperplasia symptoms: results of a national survey of physician visits / Urology 53 (5) : 921 ~ 92
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