지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 542 - 549 (8page)
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초록· 키워드
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Objectives : The present study was made to evaluate the clinical effectiveness of Saengmaeg-san (生脈散) extract to treat xerostomia in stroke patients.
Methods : The study design was a double-blind randomized controlled trial. Subjects were stroke patients with xerostomia. They were allocated to either the Saengmaeg-san (n=12) or placebo group (n=12). Saengmaeg-san extract or a placebo in similar opaque capsules was given three times a day for a week. The improvement of xerostomia was measured by the xerostomia-evaluating questionnaire, developed by the school of dentistry in Seoul National University, before baseline and one week later. Eleven of the Saengmaeg-san group and ten of the placebo group finished the trial and were analyzed. Paired samples t-test and Mann-Whitney test were applied to statistical analysis.
Results : On three of the six questions, the Saengmaeg-san group improved significantly. On two of the six questions, the Saengmaeg-san group improved significantly more than the placebo group. On the other questions, the Saengmaeg-san group improved more than the placebo group, although significance was not reached.
Conclusions : These results demonstrate that Saengmaeg-san extract is effective for treating xerostomia in stroke patients, and further studies should be conducted to provide more valuable information.
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참고문헌 (26)
참고문헌 신청
Billings RJ / 1996 / Xerostomia and associated factors in a community dwelling adults population / Community Dent Oral Epidemiol 24 : 312 ~ 316
Cassolato SF / 2003 / Xerotomia: Clinical aspects and treatment / Gerontology 20 : 64 ~ 77
Field EA / 2001 / Age and medication are significant risk factors for xerostomia in an English population, attending general dental practice / Gerontology 18 (1) : 21 ~ 24
Fox PC / 1987 / Subjective reports of xerostomia and objective measures of salivary gland performance / J Am Dent Assoc 115 : 581 ~ 584
Fox PC / 1997 / Management of dry mouth / Dent Clin North Am 41 (4) : 863 ~ 875
Cassolato SF / 2003 / Xerotomia: Clinical aspects and treatment / Gerontology 20 : 64 ~ 77
Field EA / 2001 / Age and medication are significant risk factors for xerostomia in an English population, attending general dental practice / Gerontology 18 (1) : 21 ~ 24
Fox PC / 1987 / Subjective reports of xerostomia and objective measures of salivary gland performance / J Am Dent Assoc 115 : 581 ~ 584
Fox PC / 1997 / Management of dry mouth / Dent Clin North Am 41 (4) : 863 ~ 875
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