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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 89 - 92 (4page)
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초록· 키워드
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We investigated the antioxidant and cholinesterase inhibitory activities of the aqueous extract of rainbow trout Oncorhynchus mykiss. The antioxidant activity of O. mykiss aqueous extract was determined by in vitro peroxynitrite scavenging activity and reducing power assays. The aqueous extract of O. mykiss showed potent peroxynitrite radical scavenging activity (IC_(50)=0.12±0.001 mg/mL) and reducing power (absorbance=0.47±0.001) at the concentration of 1 mg/mL. The in vitro cholinesterase inhibitory activity of O. mykiss aqueous extract was examined using spectrophotometric analyses of acetyl- and butyrylcholinesterase. The aqueous extract of O. mykiss showed acetylcholinesterase inhibitory activity (IC_(50)=1.61±0.13 mg/mL), but did not exhibit inhibitory activity against butyrylcholinesterase. These results suggest that O. mykiss possesses antioxidant and acetylcholinesterase inhibitory activities and provide scientific evidence for the health benefits of O. mykiss aqueous extract.
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참고문헌 (20)
참고문헌 신청
Association of Official Analytical Chemists / 1995 / Official Methods of Analysis.16th ed / Association of Official Analytical Chemists : 49 ~ 59
Atif F / 2006 / In vitro free radical scavenging activity of hepatic matallothionein induced in an Indian freshwater fish,Channa punctata Bloch / Chem Biol Interact 162 : 172
Bachman DL / 1992 / Prevalence of dementia and probable senile dementia of the Alzheimer type in the Framingham study / Neurololgy 42 : 115 ~ 119
Behnke RJ / 1992 / Native Trout of Western North America.American Fisheries Society Monograph 6 / Bethesda : 1 ~ 275
Ellman GL / 1961 / A new and rapid colorimetric deter-mination of acetylcholinesterase activity / Biochem Pharmacol 7 : 88 ~ 95
Atif F / 2006 / In vitro free radical scavenging activity of hepatic matallothionein induced in an Indian freshwater fish,Channa punctata Bloch / Chem Biol Interact 162 : 172
Bachman DL / 1992 / Prevalence of dementia and probable senile dementia of the Alzheimer type in the Framingham study / Neurololgy 42 : 115 ~ 119
Behnke RJ / 1992 / Native Trout of Western North America.American Fisheries Society Monograph 6 / Bethesda : 1 ~ 275
Ellman GL / 1961 / A new and rapid colorimetric deter-mination of acetylcholinesterase activity / Biochem Pharmacol 7 : 88 ~ 95
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