비인강암의 치료 성적과 예후인자 및 치료 실패의 분석

백승재; 이진석; 김귀언; 최은창; Baek; 이세영; 구본석; 이창걸; 임영창; 이원상

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자료유형: 학술저널

저자정보: 백승재 이진석 김귀언 최은창 Baek 이세영 구본석 이창걸 임영창 이원상

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제48권 제10호

발행연도: 2005.1

수록면: 1,254 - 1,260 (7page)

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Purpose：The first treatment of choice for nasopharyngeal carcinoma (NPC) is radiotherapy as NPC is more responsive to radiotherapy than any other head and neck cancer. We analyzed the clinical characteristics and prognostic factors of NPC patients treated at the Severance Hospital. Subjects and Method：Charts of 123 patients diagnosed with NPC at the Severance Hospital from 1995 to 2002 were reviewed and retrospectively analyzed. They were staged according to the 1997 AJCC criteria. According to the WHO classification, the type I included 14 cases, type II 44 cases, and type III 65 cases. Sixty-five cases were treated with radiotherapy only and 58 cases were treated with a combined modality of chemotherapy and radiotherapy. Results：The factors for a poor prognosis were age over 47 years old, histologic findings of WHO type I and advanced T, N stage. The overall 5 year survival rate was 66.22%. According to treatment modality, only the radiotherapy group was 68.6%, while the chemoradiotherapy group was 63.6%. There was no difference in survival (p>0.05). In chemoradiotherapy group, the survival of induction chemoradiotherapy group was 82.1% and the concurrent chemoradiotherapy group was 36.8%. There was significant difference in survival. Conclusions：There was no significant difference in the 5 year survival rate between the patients who were treated with radiotherapy only and those who were treated with both radiotherapy and chemotherapy.

#비인강암·치료성적·방사선치료·항암치료·예후인자. #Nasopharyngeal carcinoma·Treatment outcome·Radiotherapy·Chemotherapy·Prognostic factor.

참고문헌 (11)

참고문헌 신청

/ 1958 / Monparametric estimation from incompleteobservations 53 : 457 ~ 81

/ 1978 / The clinical and statistical study of the head andneck tumors 21 : 535 ~ 41

/ 1989 / Clinical studyof Malignant Tumors of the Nasopharynx 32 : 879 ~ 87

/ 1992 / Prognostic factors in nasopharyngealcarcinoma investigated by computer tomography - an analysisof 659 patients 23 : 79 ~ 93

/ 1992 / Retrospective analysis of 5037 patients with nasopharyngeal carcinomatreated during 1976-1985:Overall survival and patterns offailure 23 : 261 ~ 70

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