타액선 악성 종양에서 세침흡인검사 및 동결절편검사의 유용성

권성근; 서명환; 정영호; 하정훈; 김광현; 안영진; 성명훈

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자료유형: 학술저널

저자정보: 권성근 서명환 정영호 하정훈 김광현 안영진 성명훈

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제49권 제9호

발행연도: 2006.1

수록면: 922 - 927 (6page)

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Background and Objectives：The aim of this study was to investigate the efficacy of fine needle aspiration biopsy (FNAB)and frozen section biopsy in salivary gland malignancies. Subjects and Method：From January 1995 through December 2004,462 patients underwent operation for salivary gland mass. Of these patients, FNABs and frozen section biopsies were performedin 262 and 241 patients, respectively. The medical and pathologic reports were reviewed retrospectively. Malignancies were foundin 57 patients. Results：The sensitivity and the specificity of FNAB to detect salivary gland malignancies were 50.9% and 94.1%,respectively. For the frozen section biopsy, the sensitivity and specificity rose to 90.7% and 99.0%, respectively. When the examinationperiod was divided into period 1 (Jan, 1995-Dec, 1999) and period 2 (Jan, 2000-Dec, 2004), sensitivity showed asignificant increase from 33.3% to 57.1%. With respect to pathologic types of the tumors, the sensitivity of FNAB was high inadenocarcinoma (88.9%, 8/9) but low in mucoepidermoid carcinoma (30%, 3/10) and carcinoma ex pleomorphic adenoma (33.3%,3/9). Conclusion：FNAB alone cannot guarantee accurate diagnosis of salivary gland malignancies. Therefore, intraoperativefrozen section biopsy is recommended to make an adequate decision for surgical extent. The clinical experience of pathologistsis also an important factor in improving the accuracy of fine needle aspiration biopsy. (Korean J Otolaryngol 2006;49:922-7)

#타액선암종·세침흡인검사·동결절편검사. #Salivary gland neoplasms·Fine needle aspiration·Frozen sections.

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권성근

소속기관 Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea