Invasive Fungal Sinusitis of the Sphenoid Sinus

이동훈; 윤태미; 이준규; 주영은; 박경화; 임상철

추천

검색

자료유형: 학술저널

저자정보: 이동훈 윤태미 이준규 주영은 박경화 임상철

저널정보: 대한이비인후과학회 Clinical and Experimental Otorhinolaryngology Clinical and Experimental Otorhinolaryngology 제7권 제3호

발행연도: 2014.1

수록면: 181 - 187 (7page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

Objective. This study was conducted to present the clinical outcome of invasive fungal sinusitis of the sphenoid sinus and to analyze clinical factors influencing patient survival. Methods. A retrospective review of 12 cases of invasive fungal sphenoiditis was conducted. Results. Cases were divided into acute fulminant invasive fungal spheonoidits (n=4) and chronic invasive fungal sphenoid- itis (n=8). The most common underlying disease was diabetes mellitus (n=9). The most common presenting symp- toms and signs included visual disturbance (100%). Intracranial extension was observed in 8 patients. Endoscopic debridement and intravenous antifungals were given to all patients. Fatal aneurysmal rupture of the internal carotid artery occurred suddenly in two patients. The mortality rate was 100% for patients with acute fulminant invasive fungal sphenoiditis and 25% for patients with chronic invasive fungal sphenoiditis. In survival analysis, intracranial extension was evaluated as a statistically significant factor (P=0.027). Conclusion. The survival rate of chronic invasive fungal sphenoiditis was 75%. However, the prognosis of acute fulminant invasive fungal sphenoiditis was extremely poor despite the application of aggressive treatment, thus, a high index of suspicion should be required and new diagnostic markers need to be developed for early diagnosis of invasive fungal sinusitis of the sphenoid sinus.

#Invasive #Fungus #Sinusitis #Sphenoid sinus

참고문헌 (24)

참고문헌 신청

An YH / 2005 / Isolated inflammatory sphenoid sinus disease: a revisitation of computed tomography indications based on presenting findings / Am J Rhinol 19 (6) : 627 ~ 632

Aribandi M / 2007 / Imaging features of invasive and noninvasive fungal sinusitis: a review / Radiographics 27 (5) : 1283 ~ 1296

Baumann A / 2007 / Invasive sphenoidal aspergillosis: successful treatment with sphenoidotomy and voriconazole / ORL J Otorhinolaryngol Relat Spec 69 (2) : 121 ~ 126

Blitzer A / 1980 / Patient survival factors in paranasal sinus mucormycosis / Laryngoscope 90 (4) : 635 ~ 648

Chakrabarti A / 2009 / Fungal rhinosinusitis: a categorization and definitional sche-ma addressing current controversies / Laryngoscope 119 (9) : 1809 ~ 1818