Natural Course of Allergic and Nonallergic Rhinitis After 2 Years in Korean Children

이승훈; 최지호; Jeffrey D. Suh; 정소정; 홍석찬; 김진국; 조재훈

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자료유형: 학술저널

저자정보: 이승훈 최지호 Jeffrey D. Suh 정소정 홍석찬 김진국 조재훈

저널정보: 대한이비인후과학회 Clinical and Experimental Otorhinolaryngology Clinical and Experimental Otorhinolaryngology 제9권 제3호

발행연도: 2016.1

수록면: 233 - 237 (5page)

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Objectives. Allergic and nonallergic rhinitis are very common disease for children, however, little is known about their natural courses in the general population. The purpose is to evaluate the natural course of allergic and nonallergic rhinitis in children. Methods. We analyzed data from Snoring Child Cohort of 178 children (107 boys and 71 girls). All children entered the study at the age of 7 years (range, 6.5 to 7.4 years). Questionnaires regarding chronic rhinitis, a skin prick test (SPT) for 5 inhalent allergens, and specific IgE for 2 dust mites were administered. Children were classified into 4 groups: allergic rhinitis (rhinitis, positive SPT), nonallergic rhinitis (rhinitis, negative SPT), sensitization only (no rhinitis, positive SPT), and control (no rhinitis, negative SPT). We repeated follow them annually, and analyzed the data of first and third year for this study. Results. Finally, the data of 122 children were analyzed. Among 18 children with allergic rhinitis at 7 year, 13 (72%) became sensitization only after 2 years and 5 (28%) were remained having allergic rhinitis. Five out of 19 children (26%) with nonallergic rhinitis developed into allergic rhinitis and 7 (37%) into control at 9 years. Twenty-four out of 28 children (86%) with sensitization only at 7 years remained the same at 9 years. Among 57 control children at 7 year, 2 (4%) developed into allergic rhinitis, 7 (12%) with nonallergic rhinitis, and 16 (28%) with sensitization only at 9 years. Conclusion. The status of chronic rhinitis and allergen sensitization is ever-changing in children.

#Keywords. Rhinitis #Rhinitis #Allergic #Allergens #Child

참고문헌 (11)

참고문헌 신청

Strachan D. / 1997 / Worldwide variations in prevalence of symptoms of allergic rhinoconjunctivitis in children : the International Study of Asthma and Allergies in Childhood(ISAAC) / Pediatr Allergy Immunol 8(4):161~176

Tharpe CA. / 2015 / Pediatric allergic rhinitis / Immunol Allergy Clin North Am 35(1):185~198

Bousquet J. / 2008 / Allergic Rhinitis and its Impact on Asthma (ARIA) 2008 update (in collaboration with the World Health Organization, GA(2)LEN and AllerGen) / Allergy 63(Suppl 86):8~160

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Kalpaklioglu AF. / 2009 / Allergic and nonallergic rhinitis : can we find the differences/similarities between the two pictures? / J Asthma 46(5):481~485

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