폐쇄성 수면무호흡증 환자에서 신체적 특성이 수면 장애와 심혈관계합병증 발병에 미치는 영향: 예비연구

강승걸; 고재진; 예미경; 김선태; 박기형; 김지언; 신승헌

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자료유형: 학술저널

저자정보: 강승걸 고재진 예미경 김선태 박기형 김지언 신승헌

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제58권 제11호

발행연도: 2015.1

수록면: 759 - 763 (5page)

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Background and Objectives Obstructive sleep apnea (OSA) is a common yet an under-diagnosed sleep related breathing disorder associated with many adverse health outcomes. OSA is commonly associated with cardiovascular disorders that include coronary artery disease, heart failure, hypertension, cardiac arrhythmias and stroke. The aim of this study was to investigate the physical characteristics of OSA patients as a screening test for sleep apnea associated cardiovascular disease. Subjects and Method One hundred twenty-six adult OSA patients were enrolled in this study. All subjects underwent an overnight polysomnography (PSG) and were determined body mass index (BMI), neck circumstance, waist circumstance, tonsil size, etc. Cardiovascular events, such as hypertension, cardiovascular accident, myocardial infarction, and angina were analyzed. The correlation and multiple regression analysis were conducted to find influential and predictive factors of cardiovascular complications of OSA. Results PSG findings, apnea-hypopnea index (AHI), minimal oxygen saturation, and oxygen desaturation index were associated with BMI, neck circumstance, and waist circumstance. Tonsil size was also associated with AHI and oxygen desaturation index. However, PSG results were not associated with cardiovascular accidents of OSA patients. Hypertension was associated with tonsil size, angina was associated with Mallampati score and cardiovascular accident was associated with tonsil size. Conclusion Although we cannot find the statistical relation between PSG results and cardiovascular disease, tonsil size and Mallampati score influenced the risk of cardiovascular accident.

#Angina #Cardiovascular accident #Hypertension #Obstructive sleep apnea #Polysomnography

참고문헌 (20)

참고문헌 신청

Bresnitz EA / 1994 / Epidemiology of obstructive sleep apnea / Epidemiol Rev 16 (2) : 210 ~ 227

Brodsky L / 1989 / Modern assessment of tonsils and adenoids / Pediatr Clin North Am 36 (6) : 1551 ~ 1569

Davies RJ / 1990 / The relationship between neck circumference, radiographic pharyngeal anatomy, and the obstructive sleep apnoea syndrome / Eur Respir J 3 (5) : 509 ~ 514

Drager LF / 2009 / Additive effects of obstructive sleep apnea and hypertension on early markers of carotid atherosclerosis / Hypertension 53 (1) : 64 ~ 69

Jelic S / 2008 / Inflammation, oxidative stress, and repair capacity of the vascular endothelium in obstructive sleep apnea / Circulation 117 (17) : 2270 ~ 2278

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