지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 570 - 574 (5page)
이용수
초록· 키워드
오류제보하기
Background and Objectives To compare the simple spitting method and the Salivette® method of collecting saliva for detecting pepsin in patients with laryngopharyngeal reflux disease (LPRD).
Subjects and Method Thirty-two patients diagnosed with LPRD by 24 hour multichannel intraluminal impedance and pH monitoring were enrolled prospectively. The amounts of pepsin in saliva determined by the simple spitting method and the Salivette® method were compared.
Results Simple spitting showed higher sensitivity, specificity, accuracy, positive predictive value and negative predictive value. There was no statistically significant difference between the amount of pepsin detected by simple spitting (10.07±11.68 ng/mL) versus that detected using the Salivette® method (7.09±7.27 ng/mL) (p=0.258).
Conclusions The simple spitting method has higher sensitivity, specificity and accuracy than the Salivette® method for detecting pepsin in patients with LPRD.
Korean J Otorhinolaryngol-Head Neck Surg 2017;60(11):570-4
목차
등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Birti? D / 2012 / Significance of the pepsin from the saliva in the diagnosis and treatment of laryngopharyngeal reflux disease / Coll Antropol 36 (Suppl 2) : 83 ~ 86
Branski RC / 2002 / The reliability of the assessment of endoscopic laryngeal findings associated with laryngopharyngeal reflux disease / Laryngoscope 112 (6) : 1019 ~ 1024
Bulmer DM / 2010 / Laryngeal mucosa: its susceptibility to damage by acid and pepsin / Laryngoscope 120 (4) : 777 ~ 782
Carroll TL / 2012 / pH Impedance and highresolution manometry in laryngopharyngeal reflux disease highdose proton pump inhibitor failures / Laryngoscope 122 (11) : 2473 ~ 248
Johnston N / 2004 / Pepsin and carbonic anhydrase isoenzyme III as diagnostic markers for laryngopharyngeal reflux disease / Laryngoscope 114 (12) : 2129 ~ 2134
Branski RC / 2002 / The reliability of the assessment of endoscopic laryngeal findings associated with laryngopharyngeal reflux disease / Laryngoscope 112 (6) : 1019 ~ 1024
Bulmer DM / 2010 / Laryngeal mucosa: its susceptibility to damage by acid and pepsin / Laryngoscope 120 (4) : 777 ~ 782
Carroll TL / 2012 / pH Impedance and highresolution manometry in laryngopharyngeal reflux disease highdose proton pump inhibitor failures / Laryngoscope 122 (11) : 2473 ~ 248
Johnston N / 2004 / Pepsin and carbonic anhydrase isoenzyme III as diagnostic markers for laryngopharyngeal reflux disease / Laryngoscope 114 (12) : 2129 ~ 2134
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