여포 변이 유두 갑상선암: 임상 양상과 예후

정문상; 조평산; 박훈; 최익준; 이병철; 이국행; 이용식; 이명철

추천

검색

자료유형: 학술저널

저자정보: 정문상 조평산 박훈 최익준 이병철 이국행 이용식 이명철

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제54권 제8호

발행연도: 2011.1

수록면: 550 - 556 (7page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

Background and Objectives Despite relatively high incidences of follicular variant of papillary thyroid carcinoma (FV-PTC), there is a continuous debate regarding the clinical behavior, treatment outcome, prognostic variables and survival of this disease. We performed this study for the purpose of getting further understanding and more supporting ideas for the treatment of FV-PTC. Subjects and Method A clinicopathologic analysis of 116 patients who underwent a thyroidectomy with a final diagnosis of FV-PTC divided the patients into three groups: the FV-PTC only group (group A, n=78), the FV-PTC group who developed classical papillary thyroid carcinoma (C-PTC) (group B, n=38) and the C-PTC only (group C, n=320, 2003, Korea Cancer Center Hospital). The three groups were compared with respect to the following various clinicopathological characteristics: age at diagnosis, tumor size, stage of tumor, capsular invasion, age, metastasis, extent, size score, multifocality of tumor, LN metastasis, treatment, and recurrence. Results The mean tumor sizes, disease stage, and type of initial surgery were similar in three groups. However, the prevalence of nodal disease and capsular invasion were significantly higher in the groups B and C compared to the patients of group A. The 8-year disease-free survival rate was 93.7% in the patients with FV-PTC only, 90.4% in the patients with C-PTC only and 88.2% in the patients with FV-PTC group, who developed C-PTC (p >0.05). Conclusion The clinical behavior and prognosis of PTC and FV-PTC groups did not differ significantly. In treating FV-PTC, we find that it is desirable to choose a similar strategy as that used to treat C-PTC.

#Papillary thyroid carcinoma ㆍFollicular variant of papillary thyroid carcinoma ㆍPrognosis ㆍRecurrence.

참고문헌 (17)

참고문헌 신청

Baloch ZW / 1999 / Follicular variant of papillary carcinoma.Cytologic and histologic correlation / Am J Clin Pathol 111 (2) : 216 ~ 222

Baloch ZW / 2002 / Follicular-patterned lesions of the thyroid:the bane of the pathologist / Am J Clin Pathol 117 (1) : 143 ~ 150

Burningham AR / 2005 / Papillary and follicular variant of papillary carcinoma of the thyroid:initial presentation and response to therapy / Otolaryngol Head Neck Surg 132 (6

Carcangiu ML / 1985 / Papillary carcinoma of the thyroid.A clinicopathologic study of 241 cases treated at the University of Florence,Italy / Cancer 55 (4) : 805 ~ 828

Chang HY / 2006 / Clinical presentations and outcomes of surgical treatment of follicular variant of the papillary thyroid carcinomas / Jpn J Clin Oncol 36 (11) : 688 ~ 693