삼출성 중이염으로 환기관삽입술을 받은 소아에서 중이삼출액 내의 면역세포 유형과환기관 이루 발생의 관계

임길채; 현창림; 김동영; 최승효; 송찬일

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자료유형: 학술저널

저자정보: 임길채 현창림 김동영 최승효 송찬일

저널정보: 대한이비인후과학회 대한이비인후-두경부외과학회지 대한이비인후과학회지 두경부외과학 제61권 제3호

발행연도: 2018.1

수록면: 133 - 138 (6page)

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Background and ObjectivesZZTympanostomy tube insertion is one of the most commonsurgical procedures in children. Despite aseptic procedures with prophylactic antibiotic treatment,postoperative otorrhea may be encountered in some patients. The purpose of this study isto identify the relation between the types of immune cells in otitis media with effusion (OME)and tympanostomy tube otorrhea (TTO) in children. Subjects and MethodZZFifty-six patients underwent tympanostomy tube insertion withOME were analyzed retrospectively. Fluid from OME was harvested by suction via syringe connectorafter myringotomy. Light microscopic examination of middle ear effusion was performedby a pathologist after hematoxylin and eosin staining. We analyzed the relation between the typesof immune cells from middle ear effusion and TTO. ResultsZZOf 56 children, 36 were male and 22 were female. The mean age for tympanostomytube insertion was 3.56 (±2.63) years, with the average follow-up period of 12.56 (±9.96)months. Neutrophils were detected in 19, eosinophils in 14, lymphocytes in 22, mast cells in 2,plasma cells in 7, and histiocytes in 9. TTO occurred in 15 patients. In patients with early TTO,eosinophils were detected more frequently than in patients without TTO (p=0.006). Plasmacells were detected more frequently in patient with late TTO than without TTO (p=0.011). ConclusionZZAccording to the analysis of different types of immune cells, eosinophils in themiddle ear effusion related with the occurrence of TTO.

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