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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 188 - 193 (6page)
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purpose: Total knee arthroplasty (TKA) accompanies the risk of bleeding and need for transfusion. There are several methods to reduce post-operative blood loss and blood transfusion. One such method is using tranexamic acid during TKA. The purpose of this study was to confirm whether tranexamic acid reduces postoperative blood loss and blood transfusion after TKA. Materials and Methods: A total of 100 TKA patients were included in the study. The tranexamic acid group consisted of 50 patients who received an intravenous injection of tranexamic acid. The control included 50 patients who received a placebo injection. The amounts of drainage, postoperative hemoglobin, and transfusion were compared between the groups.results: The mean amount of drainage was lower in the tranexamic acid group (580.6±355.0 mL) than the control group (886.0±375.5 mL). There was a reduction in the transfusion rate in the tranexamic acid group (48%) compared with the control group (64%). The hemoglobin level was higher in the tranexamic acid group than in the control group at 24 hours postoperatively. The mean units of transfusion were smaller in the tranexamic acid group (0.76 units) than in the control group (1.28 units).conclusions: Our data suggest that intravenous injection of tranexamic acid decreases the total blood loss and transfusion after TKA.
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참고문헌 (30)
참고문헌 신청
Prasad N / 2007 / Blood loss in total knee arthroplasty : an analysis of risk factors / Int Orthop 31:39~44
Banerjee S / 2013 / Intraoperative nonpharmacotherapeutic blood management strategies in total knee arthroplasty / J Knee Surg 26:387~393
Cushner FD / 1991 / Blood loss in total knee arthroplasty / Clin Orthop Relat Res (269):98~101
Maxwell MJ / 2006 / Complications of blood transfusion / Contin Educ Anaesth Crit Care Pain 6:225~229
Bower WF / 2010 / Perioperative blood transfusion increases length of hospital stay and number of postoperative complications in non-cardiac surgical patients / Hong Kong Med J 16:116~120
Banerjee S / 2013 / Intraoperative nonpharmacotherapeutic blood management strategies in total knee arthroplasty / J Knee Surg 26:387~393
Cushner FD / 1991 / Blood loss in total knee arthroplasty / Clin Orthop Relat Res (269):98~101
Maxwell MJ / 2006 / Complications of blood transfusion / Contin Educ Anaesth Crit Care Pain 6:225~229
Bower WF / 2010 / Perioperative blood transfusion increases length of hospital stay and number of postoperative complications in non-cardiac surgical patients / Hong Kong Med J 16:116~120
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