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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 180 - 182 (3page)
이용수
초록· 키워드
오류제보하기
Lamotrigine is an anticonvulsant drug used to treat partial and generalized seizure disorders. Hypersensitivity to lamotrigine usually causes mild symptoms such as fever, rash, and slight invasion of internal organs. However, a 33-year-old male patient who was admitted with Stevens-Johnson syndrome after taking lamotrigine for 15 days experienced hepatic failure and died 5 days after admission. This case demonstrates the importance of realizing that lamotrigine can lead to fatal hepatic failure, and that tests for the normal liver function should be performed when administering lamotrigine. (Clin Mol Hepatol 2015;21:180-182)
목차
등록된 정보가 없습니다.
참고문헌 (16)
참고문헌 신청
Au JS / 2011 / Review article : Drug-induced liver injury--its pathophysiology and evolving diagnostic tools / Aliment Pharmacol Ther 34 : 11 ~ 20
Bessmertny O / 2002 / Antiepileptic hypersensitivity syndrome : clinicians beware and be aware / Curr Allergy Asthma Rep 2 : 34 ~ 39
Cheung H / 1992 / An in vitro investigation of the action of lamotrigine on neuronal voltage-activated sodium channels / Epilepsy Res 13 : 107 ~ 112
Faught E / 1999 / Adding lamotrigine to valproate: incidence of rash and other adverse effects. Postmarketing Antiepileptic Drug Survey (PADS)Group / Epilepsia 40 : 1135 ~ 1
Fayad M / 2000 / Potential hepatotoxicity of lamotrigine / Pediatr Neurol 22 : 49 ~ 52
Bessmertny O / 2002 / Antiepileptic hypersensitivity syndrome : clinicians beware and be aware / Curr Allergy Asthma Rep 2 : 34 ~ 39
Cheung H / 1992 / An in vitro investigation of the action of lamotrigine on neuronal voltage-activated sodium channels / Epilepsy Res 13 : 107 ~ 112
Faught E / 1999 / Adding lamotrigine to valproate: incidence of rash and other adverse effects. Postmarketing Antiepileptic Drug Survey (PADS)Group / Epilepsia 40 : 1135 ~ 1
Fayad M / 2000 / Potential hepatotoxicity of lamotrigine / Pediatr Neurol 22 : 49 ~ 52
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