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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 18 - 27 (10page)
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이 논문의 연구 히스토리 (2)
2014
한국인 간경변증 환자의 문맥고혈압 치료를 위한 경경정맥 간내 문맥간정맥 단락술 (TIPS)의 임상적 실제: 다기관 후향적 연구 : Clinical outcomes of transjugular intrahepatic portosystemic shunt(TIPS) for portal hypertension: Korean multicenter real practice data
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내과학
2014.01
학위논문
Clinical outcomes of transjugular intrahepatic portosystemic shunt for portal hypertension: Korean multicenter real-practice data
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Clinical and Molecular Hepatology
2014.01
학술저널
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Background/Aims: This retrospective study assessed the clinical outcome of a transjugular intrahepaticportosystemic shunt (TIPS) procedure for managing portal hypertension in Koreans with liver cirrhosis.
Methods: Between January 2003 and July 2013, 230 patients received a TIPS in 13 university-based hospitals.
Results: Of the 229 (99.6%) patients who successfully underwent TIPS placement, 142 received a TIPS for varicealbleeding, 84 for refractory ascites, and 3 for other indications. The follow-up period was 24.9±30.2 months (mean±SD),74.7% of the stents were covered, and the primary patency rate at the 1-year follow-up was 78.7%. Hemorrhageoccurred in 30 (21.1%) patients during follow-up; of these, 28 (93.3%) cases of rebleeding were associated with stentdysfunction. Fifty-four (23.6%) patients developed new hepatic encephalopathy, and most of these patients weresuccessfully managed conservatively. The cumulative survival rates at 1, 6, 12, and 24 months were 87.5%, 75.0%,66.8%, and 57.5%, respectively. A high Model for End-Stage Liver Disease (MELD) score was significantly associatedwith the risk of death within the first month after receiving a TIPS (P=0.018). Old age (P<0.001), indication for a TIPS(ascites vs. bleeding, P=0.005), low serum albumin (P<0.001), and high MELD score (P=0.006) were associated withoverall mortality.
Conclusions: A high MELD score was found to be significantly associated with early and overall mortality rate in TIPSpatients. Determining the appropriate indication is warranted to improve survival in these patients.
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참고문헌 (23)
참고문헌 신청
Blei AT / 2001 / Hepatic Encephalopathy / Am J Gastroenterol 96 : 1968 ~ 1976
Blokzijl H / 2002 / Long-term effect of treatment of acute Budd-Chiari syndrome with a transjugular intrahepatic portosytemic shunt / Hepatology 35 : 1551 ~ 1552
Boyer TD / 2005 / The role of transjugular intrahepatic portosystemic shunt in the management of portal hypertension / Hepatology 41 : 386 ~ 400
Brown DB / 2006 / Quality improvement guidelines for transhepatic arterial chemoembolization, embolization, and chemotherapeutic infusion for hepatic malignancy / J Vasc Int
Casado M / 1998 / Clinical events after transjugular intrahepatic portosystemic shunt: correlation with hemodynamic findings / Gastroenterology 114 : 1296 ~ 1303
Blokzijl H / 2002 / Long-term effect of treatment of acute Budd-Chiari syndrome with a transjugular intrahepatic portosytemic shunt / Hepatology 35 : 1551 ~ 1552
Boyer TD / 2005 / The role of transjugular intrahepatic portosystemic shunt in the management of portal hypertension / Hepatology 41 : 386 ~ 400
Brown DB / 2006 / Quality improvement guidelines for transhepatic arterial chemoembolization, embolization, and chemotherapeutic infusion for hepatic malignancy / J Vasc Int
Casado M / 1998 / Clinical events after transjugular intrahepatic portosystemic shunt: correlation with hemodynamic findings / Gastroenterology 114 : 1296 ~ 1303
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