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연세대학교 의과대학 Yonsei Medical Journal Yonsei Medical Journal 제55권 제5호
발행연도
2014.1
수록면
1,253 - 1,259 (7page)

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Purpose: This study was conducted to evaluate the surgical outcomes of active infectiveendocarditis with aortic root abscess formation. Materials and Methods: Between February 1999 and June 2012, 49 patients underwent surgery for active endocarditis with aortic root abscess. The infected valve was native in 29 patients and prosthetic in 20 patients. The patients’ mean age was 50±14 years, and 36 patientswere male. Surgery was urgent/emergent in 15 patients (31%). The abscess involved the aortic annulus (11), left ventricular outflow tract (18), fibrous trigone (16), and mitral annulus (4). In all patients, wide debridement of abscess and aortic valve replacement with or without patch reconstruction of aortic root or annulus was performed. Results: There were 6 (12%) operative deaths. Causes of early mortality were sepsis (2) and multi-organ failure (4). On postoperative echocardiogram,there was significant improvement of left ventricular dimension (LVEDD, from 58.8±11.8 mm to 52.6±8.2 mm, p<0.001); however, LV ejection fraction was significantly decreased (from 61.4±12.0% to 49.8±16.5%, p<0.001). The mean follow-up duration was 68.7±40.4 months. There was no late death or recurrent endocarditis during follow up. New York Heart Association functional class significantlyimproved from 3.2±0.7 to 1.2±0.4 (p<0.001). Kaplan-Meier estimated survivalat 10 years was 87.2%. Conclusion: Surgical treatment for active endocarditiswith aortic root abscess is still challenging, and was associated with high operative mortality. Nevertheless, long-term survival was excellent with good functional capacity after recovery from the early postoperative period.

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