지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 1,231 - 1,237 (7page)
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초록· 키워드
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Purpose: Single dose gadolinium (Gd) enhanced fluid-attenuated inversion recovery(FLAIR) is helpful for visualizing superficial parenchymal metastases. However,the usefulness of FLAIR with a higher dose of Gd is uncertain. The aim of our study was two-folds: first, to prove that the signal to noise ratio (SNR) of small brain metastases is higher than large brain metastases on double-dose (DD) enhancedFLAIR and, second, to explore the added value of DD Gd enhanced FLAIR in relation to T1 GRE for evaluating small brain metastases. Materials and Methods:For the first purpose, 50 pairs of small (2 mm<diameter≤5 mm) and large brain metastases (diameter >5 mm) were included. The difference in the SNR and contrast ratio (CR) between small and large metastases on DD Gd-enhanced 3D T2 FLAIR was compared by Wilcoxon signed-rank tests. For the second purpose, a totalof 404 small metastases were included. The diagnostic sensitivities between 3D T1 gradient echo (GRE) alone and combined results of 3D T1 GRE and 3D T2 FLAIR were compared with McNemar test. Results: The SNR and CR of small brain metastases were significantly higher than those of large brain metastases (p<0.001). In qualitative analysis, the diagnostic sensitivities for small brain metastaseswere significantly higher for 3D T1 GRE plus 3D T2 FLAIR than 3D T1 GRE alone regardless of scan time (p<0.001). Conclusion: Small brain metastases showed higher signal intensity than large brain metastases on the DD Gd enhanced 3D T2 FLAIR images. DD Gd enhanced 3D T2 FLAIR imaging may have a complementaryrole to 3D T1 GRE for evaluating small brain metastases.
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참고문헌 (24)
참고문헌 신청
Thomsen HS / 2007 / ESUR guideline: gadolinium-based contrast media and nephrogenic systemic fibrosis / Eur Radiol 17:2692~2696
Carrier DA / 1994 / Metastatic adenocarcinoma to the brain: MR with pathologic correlation / AJNR Am J Neuroradiol 15 : 155 ~ 159
Chang EL / 2003 / The role of tumor size in the radiosurgical management of patients with ambiguous brain metastases / Neurosurgery 53 : 272 ~ 280
Chang SD / 2000 / Stereoratetactic radiosurgery in patients with multiple brain metastases / Neurosurg Focus 9 : e3 ~
Davis PL / 1988 / Interactions of paramagnetic contrast agents and the spin echo pulse sequence / Invest Radiol 23 : 381 ~ 388
Carrier DA / 1994 / Metastatic adenocarcinoma to the brain: MR with pathologic correlation / AJNR Am J Neuroradiol 15 : 155 ~ 159
Chang EL / 2003 / The role of tumor size in the radiosurgical management of patients with ambiguous brain metastases / Neurosurgery 53 : 272 ~ 280
Chang SD / 2000 / Stereoratetactic radiosurgery in patients with multiple brain metastases / Neurosurg Focus 9 : e3 ~
Davis PL / 1988 / Interactions of paramagnetic contrast agents and the spin echo pulse sequence / Invest Radiol 23 : 381 ~ 388
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