메뉴 건너뛰기
Library Notice
Institutional Access
If you certify, you can access the articles for free.
Check out your institutions.
ex)Hankuk University, Nuri Motors
Log in Register Help KOR
Subject
Humanities
General Humanities History Philosophy Religious Studies Linguistics and Literature Other Humanities
Social science
General Social Science Business Management Tourism Education Military Science Library and Information Science Law Sociology Journalism and Media Studies Psychological Science Political Science and Diplomacy Geography Public Administration Economics International Trade Anthropology Other Social Science
Natural science
General Natural Science Physics Biology Life Sciences Mathematics/Statistics Astronomy Earth Science Chemistry Other Natural Science
Engineering
General Engineering Architectural Engineering Mechanical Engineering Industrial Engineering Material/Energy Engineering Electrical and Electronic Engineering Marine and Ocean Engineering Chemical Engineering Computer Science Other Engineering
Medical science
General Medical Science Nursing Science Veterinary Pharmacy Traditional Korean Medicine Basic Medicine Clinical Medicine Other Medicine
Agriculture and Fishery
General Agriculture and Fishery Agriculture Fishery Science Food Science Forestry Animal Husbandry Marine Transportation Studies Other Agriculture and Fishery
Art and Kinesiology
General Arts Design Fine Arts Cosmetology Photography Music Fashion Kinesiology Performing Media Arts Other Arts and Kinesiology
Interdisciplinary Studies
Interdisciplinary Research Science and Technology Studies Brain and Cognitive Science Technology Policy Other Interdisciplinary Studies

KOR

Serum Retinol-Binding Protein-4 Levels Are Increased in HIV-Infected Subjects with Metabolic Syndrome Receiving Highly Active Antiretroviral Therapy
Recommendations
Search

논문 기본 정보

Type
Academic journal
Author
Journal
Yonsei University College of Medicine Yonsei Medical Journal Yonsei Medical Journal 제53권 제6호 KCI Accredited Journals
Published
2012.1
Pages
1,211 - 1,215 (5page)

Usage

cover
Serum Retinol-Binding Protein-4 Levels Are Increased in HIV-Infected Subjects with Metabolic Syndrome Receiving Highly Active Antiretroviral Therapy
Ask AI
Recommendations
Search

Abstract· Keywords

Report Errors
Metabolic syndrome is an important long term complication in chronic asymptomatic HIV-infected subjects under highly active antiretroviral therapy (HAART), because it can contribute to morbidity and mortality via cardiovascular disease (CVD). Therefore, a predictive marker for early detection of metabolic syndrome may be necessary to prevent CVD in HIV-infected subjects. Retinol-binding protein-4 (RBP-4) has been shown to be associated with metabolic syndrome in various non-HIV-infected populations. We performed a cross-sectional study to evaluate whether serum RBP-4 levels are correlated with metabolic syndrome in HIV-infected subjects receiving HAART. In total, 98 HIV-infected Koreans who had been receiving HAART for at least 6 months were prospectively enrolled. Metabolic syndrome was diagnosed according to the Adult Treatment Panel III criteria, and serum RBP-4 concentrations were measured using human RBP-4 sandwich enzyme-linked immunosorbent assay. Serum RBP-4 levels were significantly higher in HIV-infected subjects receiving HAART with metabolic syndrome (n=33, 33.9±7.7 μg/mL) than in those without it (n=65, 29.9±7.2 μg/mL) (p=0.012). In multivariate linear regression analysis, the number of components of metabolic syndrome presented and waist circumference were independently, significantly correlated with RBP-4 (p=0.018 and 0.030, respectively). In conclusion, we revealed a strong correlation between RBP-4 and the number of components of metabolic syndrome in HIV-infected subjects receiving HAART.
#Retinol-binding protein-4 #metabolic syndrome #HIV #highly active antiretroviral therapy

Contents

No content found

References (19)

Add References
Aeberli I / 2007 / Serum retinol-binding protein 4 concentration and its ratio to serum retinol are associated with obesity and metabolic syndrome components in children / J google schola Barbaro G. / 2006 / Highly active antiretroviral therapy-associated metabolic syndrome: pathogenesis and cardiovascular risk / Am J Ther 13 : 248 ~ 260 google schola Bonfanti P / 2007 / HIV and metabolic syndrome: a comparison with the general population / J Acquir Immune Defic Syndr 45 : 426 ~ 431 google schola Bozzette SA / 2003 / Cardiovascular and cerebrovascular events in patients treated for human immunodeficiency virus infection / N Engl J Med 348 : 702 ~ 710 google schola Estrada V / 2006 / Lipodystrophy and metabolic syndrome in HIV-infected patients treated with antiretroviral therapy / Metabolism 55 : 940 ~ 945 google schola

Related Authors

Recently viewed articles

Shoulder Muscle Timing Pattern For High And Low Handicapped Golfers
Dong Min Shin, Chang Kook Kim, Tae Wan KimKorean Society of Sport for All1995.12
 Educational Program Model Development for Taekwondo Masters and Instructors
Cho Kwang-MinKorean Society For Sport Management1998.12

Comments(0)

0

Write first comments.