지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 1,136 - 1,141 (6page)
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Purpose: There are still debates on the benefit of mass screening for prostate cancer (PCA) by prostate specific antigen (PSA) testing, and on systemized surveillance protocols according to PSA level. Furthermore, there is a paucity of literature on current practice patterns according to PSA level in the Korean urologic field. Here, we report the results of a nationwide, multicenter, retrospective chart-review study. Materials and Methods: Overall 2122 Korean men (>40 years old, PSA >2.5 ng/mL) were included in our study (from 122 centers, in 2008). The primary endpoint was to analyze the rate of prostate biopsy according to PSA level. Secondary aims were to analyze the detection rate of PCA, the clinical features of patients,and the status of surveillance for PCA according to PSA level. Results: The rate of prostate biopsy was 7.1%, 26.3%, 54.2%, and 64.3% according to PSA levels of 2.5-3.0, 3.0-4.0, 4.0-10.0, and >10.0 ng/mL, respectively, and the PCA detection rate was 16.0%, 22.2%, 20.2%, and 59.6%, respectively. At a PSA level >4.0 ng/mL, we found a lower incidence of prostate biopsy in local clinics than in general hospitals (21.6% vs. 66.2%, respectively). A significant proportion (16.6%) of patients exhibited high Gleason scores (≥8) even in the group with low PSA values (2.5-4.0 ng/mL). Conclusion: We believe that the results from this nationwide study might provide an important database for the establishment of practical guidelines for the screening and management of PCA in Korean populations.
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참고문헌 (24)
참고문헌 신청
Andriole GL / 2009 / Mortality results from a randomized prostate-cancer screening trial / N Engl J Med 360 : 1310 ~ 1319
Brawley OW / 1997 / Prostate carcinoma incidence and patient mortality : the effects of screening and early detection / Cancer 80 : 1857 ~ 1863
Burden HP / 2008 / The trends in prostate specific antigen usage amongst United Kingdom urologists--a questionnaire based study / BMC Urol 8 : 17 ~
Catalona WJ / 1994 / Selection of optimal prostate specific antigen cutoffs for early detection of prostate cancer: receiver operating characteristic curves / J Urol 152 (6
Choi YD / 2001 / Age-specific reference ranges for serum prostate-specific antigen : community-based survey in namhae region / Korean J Urol 42 : 834 ~ 839
Brawley OW / 1997 / Prostate carcinoma incidence and patient mortality : the effects of screening and early detection / Cancer 80 : 1857 ~ 1863
Burden HP / 2008 / The trends in prostate specific antigen usage amongst United Kingdom urologists--a questionnaire based study / BMC Urol 8 : 17 ~
Catalona WJ / 1994 / Selection of optimal prostate specific antigen cutoffs for early detection of prostate cancer: receiver operating characteristic curves / J Urol 152 (6
Choi YD / 2001 / Age-specific reference ranges for serum prostate-specific antigen : community-based survey in namhae region / Korean J Urol 42 : 834 ~ 839
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