지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 279 - 288 (10page)
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초록· 키워드
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Purpose: We hypothesized that Purkinje potential and their preferential conduction to the left ventricle (LV) posteroseptum during sinus rhythm (SR) are part of reentrant circuits of idiopathic left ventricular tachycardia (ILVT) and reentry anchors to papillary muscle. Materials and Methods: In 14 patients with ILVT (11 men, mean age 31.5±11.1 years), we compared Purkinje potential and preferential conduction during SR with VT by non-contact mapping (NCM). If clear Purkinje potential(SR) was observed in the LV posteroseptum and the earliest activation site (EA) of preferential conduction at SR (EASR) was well matched with that of VT (EAVT), EASR was targeted for radiofrequency catheter ablation (RFCA). Also, the anatomical locations of successful ablation sites were evaluated by echocardiography in five additional patients. Results: 1) All induced VTs exhibited clear Purkinje potential(VT) and preferential conduction in the LV posteroseptum. The Purkinje potential(VT) and EAVT was within 5.8±8.2 mm of EASR. However, the breakout sites of VT were separated by 30.2±12.6 mm from EAVT to the apical side. 2) Purkinje potential(SR) demonstrated a reversed polarity to Purkinje potential(VT), and the interval of Purkinje potential(SR)-QRS was longer than the interval of Purkinje potential(VT)-QRS (p<0.02) 3) RFCA targeting EASR eliminated VT in all patients without recurrence within 23.3±7.5 months, and the successful ablation site was discovered at the base of papillary muscle in the five additional (100%) patients. Conclusion: NCM-guided localization of EASR with Purkinje potential(SR) matches well with EAVT with Purkinje potential(VT) and provides an effective target for RFCA, potentially at the base of papillary muscle in patients with ILVT.
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참고문헌 (21)
참고문헌 신청
Belhassen B / 1981 / Response of recurrent sustained ventricular tachycardia to verapamil / Br Heart J 46 : 679 ~ 682
Betts TR / 2000 / Radiofrequency ablation of idiopathic left ventricular tachycardia at the site of earliest activation as determined by noncontact mapping / J Cardiovasc El
Blanchard SM / 1989 / Interpolating unipolar epicardial potentials from electrodes separated by increasing distances / Pacing Clin Electrophysiol 12 : 1938 ~ 1955
Chen M / 2005 / Non-contact mapping and linear ablation of the left posterior fascicle during sinus rhythm in
Doppalapudi H / 2008 / Ventricular tachycardia originating from the posterior papillary muscle in the left ventricle: a distinct clinical syndrome / Circ Arrhythm Electrophys
Betts TR / 2000 / Radiofrequency ablation of idiopathic left ventricular tachycardia at the site of earliest activation as determined by noncontact mapping / J Cardiovasc El
Blanchard SM / 1989 / Interpolating unipolar epicardial potentials from electrodes separated by increasing distances / Pacing Clin Electrophysiol 12 : 1938 ~ 1955
Chen M / 2005 / Non-contact mapping and linear ablation of the left posterior fascicle during sinus rhythm in
Doppalapudi H / 2008 / Ventricular tachycardia originating from the posterior papillary muscle in the left ventricle: a distinct clinical syndrome / Circ Arrhythm Electrophys
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