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연세대학교 의과대학 Yonsei Medical Journal Yonsei Medical Journal 제55권 제4호
발행연도
2014.1
수록면
853 - 860 (8page)

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Currently, non-communicable chronic diseases are a major cause of morbidity and mortality worldwide, and a large proportion of chronic diseases are preventable through risk factor management. However, the prevention efficacy at the individuallevel is not yet satisfactory. Chronic disease prediction models have been developedto assist physicians and individuals in clinical decision-making. A chronic disease prediction model assesses multiple risk factors together and estimates an absolute disease risk for the individual. Accurate prediction of an individual’s futurerisk for a certain disease enables the comparison of benefits and risks of treatment,the costs of alternative prevention strategies, and selection of the most efficientstrategy for the individual. A large number of chronic disease prediction models, especially targeting cardiovascular diseases and cancers, have been suggested,and some of them have been adopted in the clinical practice guidelines and recommendations of many countries. Although few chronic disease prediction tools have been suggested in the Korean population, their clinical utility is not as high as expected. This article reviews methodologies that are commonly used for developing and evaluating a chronic disease prediction model and discusses the current status of chronic disease prediction in Korea.

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