지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 306 - 312 (7page)
이용수
초록· 키워드
오류제보하기
Purpose: We evaluated the hemodynamic statuses of patients after partial closure of atrial septal defects with fenestration due to pulmonary hypertension.
Materials and Methods: Seventeen adult patients underwent partial atrial septal defect closure and follow-up cardiac catheterization.
We analyzed hemodynamic data and clinical parameters before and after closure.
Results: The median age at closure was 29 years old. The baseline Qp/Qs was 1.9±0.6. The median interval from the operation to the cardiac catheterization was 27 months. The CT ratio decreased from 0.55±0.07 to 0.48±0.06 (p<0.05). The mean pulmonary arterial pressure decreased from 50.0±11.5 mm Hg to 32.5±14.4 mm Hg (p<0.05), and the pulmonary resistance index decreased from 9.2±3.6 Wood units*m2 to 6.3±3.8 Wood units*m2 (p<0.05). Eleven patients (64.7%) continued to exhibit high pulmonary resistance (over 3.0 Wood units*m2) after closure. These patients had significantly higher pulmonary resistance indices and mean pulmonary arterial pressures based on oxygen testing before the partial closures (p<0.05). However, no significant predictors of post-closure pulmonary hypertension were identified.
Conclusion: Despite improvement in symptoms and hemodynamics after partial closure of an atrial septal defect, pulmonary hypertensionshould be monitored carefully.
목차
등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
van Loon RL / 2011 / Pediatric pulmonary hypertension in the Netherlands: epidemiology and characterization during the period 1991 to 2005 / Circulation 124:1755~1764
Baumgartner H / 2010 / ESC Guidelines for the management of grown-up congenital heart disease (new version 2010) / Eur Heart J 31:2915~2957
Beghetti M / 2012 / Can “inoperable” congenital heart defects become operable in patients with pulmonary arterial hypertension? Dream or reality? / Congenit Heart Dis 7:3~11
Lopes AA / 2009 / Measurement, interpretation and use of hemodynamic parameters / Cardiol Young 19(Suppl 1):8~12
Hörer J / 2007 / Surgical closure of atrial septal defect in patients older than 30 years: risk factors for late death from arrhythmia or heart failure / Thorac Cardiovasc Surg 55:79~83
Baumgartner H / 2010 / ESC Guidelines for the management of grown-up congenital heart disease (new version 2010) / Eur Heart J 31:2915~2957
Beghetti M / 2012 / Can “inoperable” congenital heart defects become operable in patients with pulmonary arterial hypertension? Dream or reality? / Congenit Heart Dis 7:3~11
Lopes AA / 2009 / Measurement, interpretation and use of hemodynamic parameters / Cardiol Young 19(Suppl 1):8~12
Hörer J / 2007 / Surgical closure of atrial septal defect in patients older than 30 years: risk factors for late death from arrhythmia or heart failure / Thorac Cardiovasc Surg 55:79~83
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