지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 669 - 675 (7page)
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초록· 키워드
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Purpose: Although early neurological deterioration (END) during the acute stroke period is known to be associated with poor functional outcomes, there is little data regarding the impact of END on long-term outcomes according to the characteristicsof END. The aim of this study was to investigate whether there are differences in long-term mortality according to the characteristics of END among acute ischemicstroke or transient ischemic attack patients. Materials and Methods: END was defined as any increase (≥1) in National Institute of Health Stroke Scale score within 7 days after admission. We assessed the characteristics of END, such as the etiology and severity of END, as well as recovery after END. The relationship between30-day or long-term mortality and each characteristic of END was investigatedusing multiple logistic analysis or Cox regression model. Results: Among 2820 patients, END was observed in 344 patients (12.2%). After adjustment for age, sex, underlying cardiovascular diseases, stroke severity, and stroke subtypes, END was associated with long-term mortality, whether it was mild or severe and whether or not it was followed by recovery. However, 30-day mortality was stronglyrelated to the severity of END or the absence of recovery after END. Among the causes of END, recurrent stroke and medical illness were related to 30-day mortality,as well as long-term mortality, while brain herniation and intracranial hemorrhagiccomplications were only associated with 30-day mortality. Conclusion: The results of the present study demonstrated that END is associated with higher mortalityand the effects of END on short-term and long-term mortality depend on END characteristics.
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등록된 정보가 없습니다.
참고문헌 (22)
참고문헌 신청
Adams HP Jr / 1999 / Baseline NIH Stroke Scale score strongly predicts outcome after stroke: a report of the Trial of Org 10172 in Acute Stroke Treatment (TOAST) / Neurology
Appelros P / 2003 / Poor outcome after first-ever stroke: predictors for death, dependency, and recurrent stroke within the first year / Stroke 34 : 122 ~ 126
Barber M / 2006 / D-dimer predicts early clinical progression in ischemic stroke: confirmation using routine clinical assays / S
Birschel P / 2004 / Progressing stroke: towards an internationally agreed definition / Cerebrovasc Dis 17 : 242 ~ 252
Chang KC / 2010 / Three-year survival after first-ever ischemic stroke is predicted by initial stroke severity: a hospital-based study / Clin Neurol Neurosurg 112 : 296 ~ 301
Appelros P / 2003 / Poor outcome after first-ever stroke: predictors for death, dependency, and recurrent stroke within the first year / Stroke 34 : 122 ~ 126
Barber M / 2006 / D-dimer predicts early clinical progression in ischemic stroke: confirmation using routine clinical assays / S
Birschel P / 2004 / Progressing stroke: towards an internationally agreed definition / Cerebrovasc Dis 17 : 242 ~ 252
Chang KC / 2010 / Three-year survival after first-ever ischemic stroke is predicted by initial stroke severity: a hospital-based study / Clin Neurol Neurosurg 112 : 296 ~ 301
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