지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 1,562 - 1,567 (6page)
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초록· 키워드
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Purpose: This study investigated the possible relationship between viral infection and first trimester pregnancy loss. Materials and Methods: A prospective study was performed on 51 gravidas with missed abortion, fetal anomaly, pre-term delivery,and full-tem delivery at Hanyang University Hospital. Enteroviruses were detectedby semi-nested reverse transcription-polymerase chain reaction (RT-PCR) and immunohistochemistry in abortive tissues and placentas. Enterovirus serotypes were confirmed by genome sequencing. Herpesviruses were detected by PCR. Results:Coxsackievirus B3 (CVB3) was detected in 8 of 14 missed abortion cases, 1 of 27 full-term cases, and none of the 9 pre-term cases. Coxsackievirus B1 (CVB1) was detected in an encephalocele case. Herpes simplex virus type 1 was found in 4 full-term cases, 3 pre-term cases, and none of the missed abortion cases. Conclusion:The prevalence of CVB3 was significantly higher in missed abortion cases compared to full-term or pre-term delivery cases. CVB infection may therefore be an important etiological agent of missed abortion.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Asher DR / 2005 / Coxsackievirus and adenovirus receptor is essential for cardiomyocyte development / Genesis 42 : 77 ~ 85
Avgil M / 2006 / Herpes simplex virus and Epstein-Barr virus infections in pregnancy: consequences of neonatal or intrauterine infection / Reprod Toxicol 21 : 436 ~ 445
Axelsson C / 1993 / Coxsackie B virus infections in women with miscarriage / J Med Virol 39 : 282 ~ 285
Basso NG / 1990 / Enterovirus isolation from foetal and placental tissues / Acta Virol 34 : 49 ~ 57
Bendig JW / 2003 / Coxsackievirus B3 sequences in the blood of a neonate with congenital myocarditis, plus serological evidence of maternal infection / J Med Virol 70 : 606 ~
Avgil M / 2006 / Herpes simplex virus and Epstein-Barr virus infections in pregnancy: consequences of neonatal or intrauterine infection / Reprod Toxicol 21 : 436 ~ 445
Axelsson C / 1993 / Coxsackie B virus infections in women with miscarriage / J Med Virol 39 : 282 ~ 285
Basso NG / 1990 / Enterovirus isolation from foetal and placental tissues / Acta Virol 34 : 49 ~ 57
Bendig JW / 2003 / Coxsackievirus B3 sequences in the blood of a neonate with congenital myocarditis, plus serological evidence of maternal infection / J Med Virol 70 : 606 ~
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