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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 1,322 - 1,327 (6page)
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초록· 키워드
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Purpose: Leptomeningeal collateral, in moyamoya disease (MMD), appears as an ivy sign on fluid-attenuated inversion-recovery (FLAIR) images. There has been little investigation into the relationship between presentation of ivy signs and old brain lesions. We aimed to evaluate clinical significance of ivy signs and whether they correlate with old brain lesions and the severity of clinical symptoms in patients with MMD.
Materials and Methods: FLAIR images of 83 patients were reviewed. Each cerebral hemisphere was divided into 4 regions and each region was scored based on the prominence of the ivy sign. Total ivy score (TIS) was defined as the sum of the scores from the eight regions and dominant hemispheric ivy sign (DHI) was determined by comparing the ivy scores from each hemisphere. Accordingto the degree of ischemic symptoms, patients were classified into four subgroups: 1) nonspecific symptoms without motorweakness, 2) single transient ischemic attack (TIA), 3) recurrent TIA, or 4) complete stroke.
Results: TIS was significantly different as follows: 4.86±2.55 in patients with nonspecific symptoms, 5.89±3.10 in patients with singleTIA, 9.60±3.98 in patients with recurrent TIA and 8.37±3.39 in patients with complete stroke (p=0.003). TIS associated with old lesions was significantly higher than those not associated with old lesions (9.35±4.22 vs. 7.49±3.37, p=0.032). We found a significant correlation between DHI and motor symptoms (p=0.001).
Conclusion: Because TIS has a strong tendency with severity of ischemic motor symptom and the presence of old lesions, the ivy sign may be useful in predicting severity of disease progression.
목차
등록된 정보가 없습니다.
참고문헌 (15)
참고문헌 신청
/ 2012 / Research Committee on the Pathology and Treatment of Spontaneous Occlusion of the Circle of Willis; Health Labour Sciences Research Grant for Research on Measures f
Fujiwara H / 2005 / Leptomeningeal high signal intensity (ivy sign) on fluid-attenuated inversion-recovery (FLAIR) MR images in moyamoya disease / Eur J Radiol 55 : 224 ~ 230
Fukui M / 1997 / Guidelines for the diagnosis and treatment of spontaneous occlusion of the circle of Willis (‘moyamoya’ disease). Research Committee on Spontaneous Occlus
Hoshino H / 2012 / Epidemiological features of moyamoya disease in Japan / Neurol Med Chir (Tokyo) 52 : 295 ~ 298
Ishikawa T / 2005 / Prevalence of asymptomatic microbleeds in patients with moyamoya disease / Neurol Med Chir (Tokyo) 45 : 495 ~ 500
Fujiwara H / 2005 / Leptomeningeal high signal intensity (ivy sign) on fluid-attenuated inversion-recovery (FLAIR) MR images in moyamoya disease / Eur J Radiol 55 : 224 ~ 230
Fukui M / 1997 / Guidelines for the diagnosis and treatment of spontaneous occlusion of the circle of Willis (‘moyamoya’ disease). Research Committee on Spontaneous Occlus
Hoshino H / 2012 / Epidemiological features of moyamoya disease in Japan / Neurol Med Chir (Tokyo) 52 : 295 ~ 298
Ishikawa T / 2005 / Prevalence of asymptomatic microbleeds in patients with moyamoya disease / Neurol Med Chir (Tokyo) 45 : 495 ~ 500
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