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Purpose: Upper extremity musculoskeletal disorders (UEMDs), such as rotator cuff tear, epicondylitis, and hand osteoarthritis,have a negative impact on quality of life (QOL). In this study, we evaluated the prevalence of rotator cuff tear, lateral and medialepicondylitis, and hand osteoarthritis in the dominant side and the impact of these UEMDs on the disabilities of the arm, shoulder,and hand (DASH) outcome measure, which assesses upper extremity-related QOL. Materials and Methods: In 2013−2015, 987 participants from rural areas completed a questionnaire and underwent physical examinations,laboratory tests, simple radiographic evaluations of bilateral upper extremities, and magnetic resonance imagingstudies of bilateral shoulders. Based on data from these participants, researchers evaluated DASH and performed a functional assessmentof each region of the dominant side and related UEMDs. Results: The prevalences of epicondylitis, rotator cuff tear, and hand osteoarthritis were 33.7%, 53.4%, and 44.6%, respectively. Univariate regression analysis results revealed that epicondylitis, epicondylitis+rotator cuff tear, epicondylitis+hand osteoarthritis,and epicondylitis+rotator cuff tear+hand osteoarthritis were significantly associated with DASH score. Multiple regressionanalysis, including DASH, UEMD, and regional functional assessments, showed that only epicondylitis and epicondylitis+rotatorcuff tear were associated with DASH score. Conclusion: Epicondylitis significantly affected QOL, while other UEMDs, such as hand osteoarthritis and rotator cuff tear, hadno significant impact. When a patient’s QOL is affected by a UEMD, there is an increased possibility of the simultaneous presenceof other UEMDs.

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