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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 72 - 81 (10page)
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초록· 키워드
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Purpose: Several endoscopic resection therapies have been applied for the treatment of rectal carcinoid tumors. However, there is currently no consensus regarding the optimal strategy. We performed a meta-analysis to compare the efficacy and safety of endoscopic mucosal resection (EMR) or modified EMR (m-EMR) versus endoscopicsubmucosal dissection (ESD) for the treatment of rectal carcinoid tumors. Materials and Methods: PubMed, Web of Science, Medline, Embase and CNKI were searched up to the end of January 2014 in order to identify all studies on the effectsof EMR (or m-EMR) and ESD on rectal carcinoid tumors. Results: A total of fourteen studies involving 782 patients were included. The pooled data suggested a significantly higher rate of pathological complete resection among patients treated with ESD or m-EMR than those treated with EMR [odds ratio (OR)=0.42, 95% confidenceinterval (CI): 0.25‒0.71; OR=0.10, 95% CI: 0.03‒0.33, respectively], while there was no significant difference between the m-EMR group and ESD group (OR=1.19, 95% CI: 0.49‒2.86); The procedure time of ESD was longer than EMR or m-EMR groups [mean differences (MD)=-11.29, 95% CI: -14.19 ‒ -8.38, MD= -10.90, 95% CI: -18.69 ‒ -3.11, respectively], but it was insignificance between the EMR and m-EMR groups. No significant differences were detected among the treatmentgroups with regard to complications or recurrence. Conclusion: The results of this meta-analysis suggest that treatment of rectal carcinoid tumors with ESD or m-EMR is superior to EMR, and the efficacy of m-EMR is equivalence to ESD treatment.
However, more well-designed studies are needed to confirm these findings.
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참고문헌 (24)
참고문헌 신청
Baek IH / 2010 / Endoscopic submucosal dissection or conventional endoscopic mucosal resection is an effective and safe treatment for rectal carcinoid tumors: a retrospective
Begg CB / 1994 / Operating characteristics of a rank correlation test for publication bias / Biometrics 50 : 1088
Caplin M / 2012 / ENETS Consensus Guidelines for the management of patients with digestive neuroendocrine neoplasms: colorectal neuroendocrine neoplasms / Neuroendocrinology
Choi CW / 2013 / Comparison of endoscopic resection therapies for rectal carcinoid tumor: endoscopic submucosal dissection versus endoscopic mucosal resection using band liga
DerSimonian R / 1986 / Meta-analysis in clinical trials / Control Clin Trials 7 : 177 ~ 188
Begg CB / 1994 / Operating characteristics of a rank correlation test for publication bias / Biometrics 50 : 1088
Caplin M / 2012 / ENETS Consensus Guidelines for the management of patients with digestive neuroendocrine neoplasms: colorectal neuroendocrine neoplasms / Neuroendocrinology
Choi CW / 2013 / Comparison of endoscopic resection therapies for rectal carcinoid tumor: endoscopic submucosal dissection versus endoscopic mucosal resection using band liga
DerSimonian R / 1986 / Meta-analysis in clinical trials / Control Clin Trials 7 : 177 ~ 188
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