지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 127 - 131 (5page)
이용수
초록· 키워드
오류제보하기
Purpose: This study examined the outcomes of children with chronic immune thrombocytopenia (ITP).
Materials and Methods: We retrospectively analyzed the medical records of all patients diagnosed with ITP from January 1992 to December 2011 at our institution.
Results: A total of 128 patients (64%) satisfied the criteria for newly diagnosed ITP, 31 (15%) for persistent ITP, and 41 (21%) for chronic ITP. The median age at diagnosis was 4.5 years (range, 1 month to 18 years). The median platelet count at diagnosis was 32×109/L. A comparison of the initial treatment data from 2001 to 2011 with those from 1992 to 2000 showed that the number of bone marrow examinations decreased, whereas observation increased. Chronic ITP presented at an older age than newly diagnosed and persistent ITP (6.6 years vs. 3.8 years vs. 4.1 years, respectively); however, the difference did not reach statistical significance (p=0.17). The probability of complete remission of chronic ITP was 50% and 76% at 2 and 5 years after diagnosis, respectively. Patientsaged <1 year at diagnosis had a significantly better prognosis than did older patients (hazard ratio, 3.86; p=0.02).
Conclusion: Children with chronic ITP showed a high remission rate after long-term follow-up. This study suggests that invasive treatments such as splenectomy in children with chronic ITP can be delayed for 4 to 5 years if thrombocytopenia and therapeutic medication do not affect the quality of life.
목차
등록된 정보가 없습니다.
참고문헌 (24)
참고문헌 신청
[학술지
Ahn YS / 1984 / Slow infusion of vinca alkaloids in the treatment of idiopathic thrombocytopenic purpura / Ann Intern Med 100 : 192 ~ 196
Bansal D / 2010 / Outcome of chronic idiopathic thrombocytopenic purpura in children / Pediatr Blood Cancer 54 : 403 ~ 407
Bolton-Maggs PH / 2000 / Idiopathic thrombocytopenic purpura / Arch Dis Child 83 : 220 ~ 222
British Committee for Standards in Haema / 2003 / Guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults, children and in pregnancy
Ahn YS / 1984 / Slow infusion of vinca alkaloids in the treatment of idiopathic thrombocytopenic purpura / Ann Intern Med 100 : 192 ~ 196
Bansal D / 2010 / Outcome of chronic idiopathic thrombocytopenic purpura in children / Pediatr Blood Cancer 54 : 403 ~ 407
Bolton-Maggs PH / 2000 / Idiopathic thrombocytopenic purpura / Arch Dis Child 83 : 220 ~ 222
British Committee for Standards in Haema / 2003 / Guidelines for the investigation and management of idiopathic thrombocytopenic purpura in adults, children and in pregnancy
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
IVIG Treatment Response and Age are Important for the Prognosis of Pediatric Immune Thrombocytopenia
Clinical Pediatric Hematology-Oncology
2022 .10
-
Diagnostic Approach of Childhood Immune Thrombocytopenia
Clinical Pediatric Hematology-Oncology
2018 .01
-
Management of immune thrombocytopenia: Korean experts recommendation in 2017
Blood Research
2017 .01
-
Life-threating outcomes after dental implantation in patient with idiopathic thrombocytopenic purpura: a case report and review of literature
Maxillofacial Plastic Reconstructive Surgery
2018 .12
-
Recent advances in treatments of adult immune thrombocytopenia
Blood Research
2022 .04
-
Efficacy and Safety of a New 10% Intravenous Immunoglobulin Product in Patients with Primary Immune Thrombocytopenia (ITP)
Journal of Korean Medical Science
2018 .01
-
Management of immune thrombocytopenia: 2022 update of Korean experts recommendations
Blood Research
2022 .03
-
Interleukin-1B (IL-1B-31 and IL-1B-511) and interleukin-1 receptor antagonist (IL-1Ra) gene polymorphisms in primary immune thrombocytopenia
Blood Research
2017 .01
-
Association of CD40 gene polymorphisms and immune thrombocytopenic purpura in the adult Egyptian population
Blood Research
2022 .09
-
A Case Report of Immune Thrombocytopenia after ChAdOx1 nCoV-19 Vaccination
Journal of Korean Medical Science
2021 .11
-
Cytotoxic T lymphocyte‐associated antigen‐4 (CTLA‑4) gene polymorphisms in a cohort of Egyptian patients with immune thrombocytopenia (ITP)
Blood Research
2024 .03
-
면역성혈소판감소증을 동반한 사르코이드증
영남의대학술지
2015 .01
-
면역성혈소판감소증을 동반한 사르코이드증
Journal of Yeungnam Medical Science
2015 .06
-
Successful kidney transplantation from a live donor with immune thrombocytopenia: a case report
Clinical Transplantation and Research
2024 .06
-
Recurrent Cerebral Infarctions and Multi-Vessel Thrombosis in a Male Patient with Refractory Idiopathic Thrombocytopenic Purpura: a Case Report
뇌신경재활
2021 .01
-
Effect of short-term, high-dose methylprednisolone on oxidative stress in children with acute immune thrombocytopenia
Blood Research
2016 .01
-
Beta-Thalassemia with Initial Presentation as Immune Thrombocytopenia: A Case Report
Clinical Pediatric Hematology-Oncology
2023 .04
-
Clinical characteristics and treatment courses for cytomegalovirus-associated thrombocytopenia in immunocompetent children after neonatal period
Blood Research
2018 .01
-
녹용대보탕을 투여한 ITP 의증 환자 증례보고
대한한방내과학회지
2021 .10
-
Platelet count recovery after intravenous immunoglobulin predicts a favorable outcome in children with immune thrombocytopenia
Blood Research
2016 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0