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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 936 - 941 (6page)
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초록· 키워드
오류제보하기
Purpose: The efficacy of helmet continuous positive airway pressure (CPAP) in hypoxemic acute respiratory failure (hARF) remainsunclear. The aim of this meta-analysis was to critically review studies that investigated the effect of helmet CPAP on gas exchange,mortality, and intubation rate in comparison with standard oxygen therapy.
Materials and Methods: We performed a meta-analysis of randomized controlled trials (RCTs) by searching the PubMed, Embase,Cochrane library, OVID, and CBM databases, and the bibliographies of the retrieved articles. Studies that enrolled adults with hARF who were treated with helmet CPAP and measured at least one of the following parameters were included: gas exchange,intubation rate, in-hospital mortality rate.
Results: Four studies with 377 subjects met the inclusion criteria and were analyzed. Compared to the standard oxygen therapy, helmet CPAP significantly increased the PaO2/FiO2 [weighted mean difference (WMD)=73.40, 95% confidence interval (95% CI): 43.92 to 102.87, p<0.00001], and decreased the arterial carbon dioxide levels (WMD=-1.92, 95% CI: -3.21 to -0.63, p=0.003), intubationrate [relative risk (RR)=0.21, 95% CI: 0.11 to 0.40, p<0.00001], and in-hospital mortality rate (RR=0.22, 95% CI: 0.09 to 0.50, p=0.0004).
Conclusion: The results of this meta-analysis suggest that helmet CPAP improves oxygenation and reduces mortality and intubationrates in hARF. However, the significant clinical and statistical heterogeneity of the literature implies that large RCTs are neededto determine the role of helmet CPAP in different hypoxemic ARF populations.
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등록된 정보가 없습니다.
참고문헌 (30)
참고문헌 신청
Esquinas Rodriguez AM / 2013 / Clinical review: helmet and non-invasive mechanical ventilation in critically ill patients / Crit Care 17:223
Mehta S / 2001 / Noninvasive ventilation / Am J Respir Crit Care Med 163:540~577
Hillberg RE / 1997 / Noninvasive ventilation / N Engl J Med 337:1746~1752
Mas A / 2014 / Noninvasive ventilation in acute respiratory failure / Int J Chron Obstruct Pulmon Dis 9:837~852
Delclaux C / 2000 / Treatment of acute hypoxemic nonhypercapnic respiratory insufficiency with continuous positive airway pressure delivered by a face mask: a randomized controlled trial / JAMA 284:2352~2360
Mehta S / 2001 / Noninvasive ventilation / Am J Respir Crit Care Med 163:540~577
Hillberg RE / 1997 / Noninvasive ventilation / N Engl J Med 337:1746~1752
Mas A / 2014 / Noninvasive ventilation in acute respiratory failure / Int J Chron Obstruct Pulmon Dis 9:837~852
Delclaux C / 2000 / Treatment of acute hypoxemic nonhypercapnic respiratory insufficiency with continuous positive airway pressure delivered by a face mask: a randomized controlled trial / JAMA 284:2352~2360
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