지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 1,038 - 1,041 (4page)
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Brown adipose tissue (BAT) is related with energy expenditure, in contrary to fat-storing white adipose tissue. Recent studies have shown that cold exposure could be related with the expression of BAT in adult subjects assessed by 18F-fluorodeoxyglucose (FDG) positron emission tomography (PET). In addition, the application in previous clinical trials showed positive effect of xanthigen containing fucoxanthin and punicic acid on body weight and liver fat content. In this short-term intervention study, we evaluated the effect of xanthigen on the expression of BAT by 18F-FDG PET. Two healthy obese premenopausal women were enrolled and xanthigen 600 mg (2 capsules including fucoxanthin 3 mg, punicic acid 174 mg) was given for 3 months without dietary and exerciseintervention. Body composition and dietary intake were assessed monthly. Laboratory test and 18F-FDG PET were performed before and after intervention. After intervention, there was neither weight reduction nor remarkable laboratory change. However, BAT, assessed by 18F-FDG PET, was detected in both cervical, supraclavicular and paravertebral space in one subject, even though her body weight showed mild increase. This result suggested that xanthigen can induce BAT in a healthy adult. However, a further large well-controlled study is needed.
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등록된 정보가 없습니다.
참고문헌 (16)
참고문헌 신청
van Marken Lichtenbelt WD / 2009 / Cold-activated brown adipose tissue in healthy men / N Engl J Med 360:1500~1508
Yoneshiro T / 2011 / Brown adipose tissue, whole-body energy expenditure, and thermogenesis in healthy adult men / Obesity (Silver Spring) 19:13~16
Maeda H / 2005 / Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues / Biochem Biophys Res Commun 332:392~397
Abidov M / 2010 / The effects of Xanthigen in the weight management of obese premenopausal women with non-alcoholic fatty liver disease and normal liver fat / Diabetes Obes Metab 12:72~81
Wu J / 2012 / Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human / Cell 150:366~376
Yoneshiro T / 2011 / Brown adipose tissue, whole-body energy expenditure, and thermogenesis in healthy adult men / Obesity (Silver Spring) 19:13~16
Maeda H / 2005 / Fucoxanthin from edible seaweed, Undaria pinnatifida, shows antiobesity effect through UCP1 expression in white adipose tissues / Biochem Biophys Res Commun 332:392~397
Abidov M / 2010 / The effects of Xanthigen in the weight management of obese premenopausal women with non-alcoholic fatty liver disease and normal liver fat / Diabetes Obes Metab 12:72~81
Wu J / 2012 / Beige adipocytes are a distinct type of thermogenic fat cell in mouse and human / Cell 150:366~376
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