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연세대학교 의과대학 Yonsei Medical Journal Yonsei Medical Journal 제59권 제1호
발행연도
2018.1
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107 - 112 (6page)

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Purpose: Contrast-induced acute kidney injury (CI-AKI) is associated with poor outcomes after percutaneous coronary intervention. However, CI-AKI has rarely been evaluated within the neurovascular field. The aim of this study was to investigate the incidenceand clinical implication of CI-AKI after coil embolization in patients with an aneurysmal subarachnoid hemorrhage (aSAH). Materials and Methods: Between January 2005 and March 2016, 192 patients who underwent coil embolization were enrolled in this study. CI-AKI was defined as an increase from baseline serum creatinine concentration of >25% or >0.5 mg/dL within 72 hours after coil embolization. A poor clinical outcome was defined as a score of ≥3 on the modified Rankin Scale at one-year post-treatment. Results: A total of 16 patients (8.3%) died as a result of medical problems within one year. CI-AKI was identified in 14 patients (7.3%). Prominent risk factors for one-year mortality included CI-AKI [odds ratio (OR): 16.856; 95% confidence interval (CI): 3.437−82.664] and an initial Glasgow Coma Scale (GCS) score ≤8 (OR: 5.565; 95% CI: 1.703−18.184). A poor clinical outcome was associated with old age (≥65 years) (OR: 7.921; 95% CI: 2.977−21.076), CI-AKI (OR: 11.281; 95% CI: 2.138−59.525), an initial GCS score ≤8 (OR 31.02; 95% CI, 10.669−90.187), and a ruptured aneurysm (p=0.016, OR: 4.278) in posterior circulation. Conclusion: CI-AKI seems to be an independent predictor of the overall outcomes of aSAH after endovascular treatment.

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