지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 768 - 772 (5page)
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초록· 키워드
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Purpose: To determine the ability of a novel palpation device to differentiate between benign and malignant tissues of the kidney and bladder by measuring tissue elasticity. Materials and Methods: A novel palpation device was developed, mainly composed of a micromotor, a linear position sensor, a force transducer, and a hemisphere tip and cylindrical body probe. Motion calibration as well as performance validation was done. The tissue elasticity of both benign and malignant tissues of the kidney and bladder was measured using this device. A single investigator performed the ex-vivo palpation experiment in twelve kidneys and four bladder specimens. Malignant tissues were made available from partial nephrectomy specimens and radical cystectomy specimens. Palpations for benign renal parenchyma tissue were carried out on nephroureterectomy specimens while non-involved areas in the radical cystectomy specimens were used for benign bladder samples. Elastic modulus (Young’s modulus) of tissues was estimated using the Hertz-Sneddon equation from the experimental results. These were then compared using a t-test for independent samples. Results: Renal cell carcinoma tissues appear to be softer than normal kidney tissues, whereas tissues from urothelial carcinoma of the bladder appear to be harder than normal bladder tissues. The results from renal cell carcinoma differed significantly from those of normal kidney tissues (p=0.002), as did urothelial carcinoma of the bladder from normal bladder tissues (p=0.003). Conclusion: Our novel palpation device can potentially differentiate between malignant and benign kidney and bladder tissues. Further studies are necessary to verify our results and define its true clinical utility.
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참고문헌 (12)
참고문헌 신청
Allaparthi S / 2010 / Robotic partial cystectomy for bladder cancer: a single-institutional pilot study / J Endourol 24 : 223 ~ 227
Clevert DA / 2009 / Evaluation of Acoustic Radiation Force Impulse (ARFI) imaging and contrast-enhanced ultrasound in renal tumors of unknown etiology in comparison to histo
Fahey BJ / 2008 / In vivo visualization of abdominal malignancies with acoustic radiation force elastography / Phys Med Biol 53 : 279 ~ 293
Gravas S / 2009 / Advances in ultrasound technology in oncologic urology / Urol Clin North Am 36 : 133 ~ 145
Kaul S / 2007 / da Vinci-assisted robotic partial nephrectomy: technique and results at a mean of 15 months of follow-up / Eur Urol 51 : 186 ~ 191
Clevert DA / 2009 / Evaluation of Acoustic Radiation Force Impulse (ARFI) imaging and contrast-enhanced ultrasound in renal tumors of unknown etiology in comparison to histo
Fahey BJ / 2008 / In vivo visualization of abdominal malignancies with acoustic radiation force elastography / Phys Med Biol 53 : 279 ~ 293
Gravas S / 2009 / Advances in ultrasound technology in oncologic urology / Urol Clin North Am 36 : 133 ~ 145
Kaul S / 2007 / da Vinci-assisted robotic partial nephrectomy: technique and results at a mean of 15 months of follow-up / Eur Urol 51 : 186 ~ 191
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