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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 32 - 40 (9page)
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초록· 키워드
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Objectives : Hyaluronic acid(HA) is a mucopolysaccharide, occuring naturally in living organisms. It is one of themost hydrophilic molecules, so it has been known as being related to skin hydration and anti-aging. The purposeof this study is to examine the effects of Angelica acutiloba ethanol extract on hyaluronic acid synthesis.
Methods : To determine cytotoxicity and hyaluronic acid synthase 2 gene expression, hyaluronic acid productionin HaCaT cells, MTT assay and RT-PCR ELISA was used.
Results : There was no cytotoxicity in 50㎍/㎖ concentration Angelica acutiloba extract in MTT assay. Hyaluronic acidsynthase 2(HAS2) gene expression was increased by all treated concentration Angelica acutiloba extract. Hyaluronicacid production was higher in 50㎍/㎖ & 100㎍/㎖ concentration Angelica acutiloba extract than control group.
Conclusions : Hyaluronic acid production was increased by Angelica Acutiloba extracts. Therefore, We suggestthat Angelica acutiloba can make a contribution to the moisturing effect on human skin.Conclusions : Hyaluronicacid production was increased by Angelica Acutiloba extracts. Therefore, We suggest that Angelica acutiloba canmake a contribution to the moisturing effect on human skin.
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참고문헌 (31)
참고문헌 신청
KDA Textbook Editing Board / 2014 / Dermatology / Medbook : 697 ~ 964
Kang BS / 2008 / Herbal Medicine of the World in Color / Dongamunhwasa : 168 ~ 173
Kim SH / 2005 / The Effect of Kaempferol, Quercetin on Hyaluronan-Synthesis Stimulation in Human Keratinocyte (HaCaT) / J Soc Cosmet Scientists Korea 31 (1) : 97 ~ 102
Kim SJ / 2004 / Compound K induces expression of hyaluronan synthase 2 gene in transformed human keratinocytes and increases hyaluronan in hairless mouse skin / Biochemical
Necas J / 2008 / Hyaluronic acid (Hyaluronan): a review / Veterinarni Medicina 53 (3) : 397 ~ 411
Kang BS / 2008 / Herbal Medicine of the World in Color / Dongamunhwasa : 168 ~ 173
Kim SH / 2005 / The Effect of Kaempferol, Quercetin on Hyaluronan-Synthesis Stimulation in Human Keratinocyte (HaCaT) / J Soc Cosmet Scientists Korea 31 (1) : 97 ~ 102
Kim SJ / 2004 / Compound K induces expression of hyaluronan synthase 2 gene in transformed human keratinocytes and increases hyaluronan in hairless mouse skin / Biochemical
Necas J / 2008 / Hyaluronic acid (Hyaluronan): a review / Veterinarni Medicina 53 (3) : 397 ~ 411
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