지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한치매학회 Dementia and Neurocognitive Disorders(대한치매학회지) Dementia and Neurocognitive Disorders(대한치매학회지) 제11권 제4호
- 발행연도
- 2012.1
- 수록면
- 124 - 130 (7page)
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초록· 키워드
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Background: With the ageing population, number of dementia patients is on the rise, as well as the public interest. The population who would visit memory disorder clinic will also grow. The diagnostic significance of brain MRI in dementia lies in idetifying hippocampal atrophy or ischemic lesions. However, patients visiting memory disorder clinic are mostly old-aged with multiple vascular risk factors, raising the risk of cerebrovascular abnormalities. The authors set out to evaluate the need for cerebrevascular imaging in patients who visited memory disorder clinic. Methods: The study recruited patients who visited the memory clinic in Seoul medical center between July 2011 and June 2012. Among those, patients who had taken the neuropsychiatric test and had both brain MRI and MRA taken were included for analysis. In brain MRI, severities of white matter hyperintensities and presence of cerebral infarction were assessed. In brain MRA, intra- and extra-cranial arterial stenosis and presence of aneurysm were noted. Results: A total of 173 patients was included, and 64 were men. The mean age was 71±9.4 years, and the mean education period was 7±5.2 years. In brain MRI, white matter hyperintensities were observed in 113 patients (65.3%), and cerebral infarction was present in 57 patients (32.9%). In brain MRA, 88 (50.9%) patients showed more than one stenotic segment in intracranial vessel or proximal ICA and 6 patients (3.5%) were diagnosed with unruptured aneurysm. Conclusions: The incidence of white matter hyperintensities or stenosis of cerebral vessels on magnetic resonance imaging is very high. Therefore, brain MRI and MRA should be included in diagnostic work up for dementia in patients who are old aged and have multiple vascular risk factors. It would provide clinicians with valuable information in making treatment decisions and prevention of future cerebrovascular accident.
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참고문헌 (23)
참고문헌 신청
Fazekas F / 1987 / MR signal abnormalities at 1.5T in Alzheimer’s dementia and normal aging / AJR 149 : 351 ~ 356
Heiserman J / 1992 / Intracranial vascular stenosis and occlusion: evaluation with three-dimentional time-of-flight MR angiography / Radiology 185 : 667 ~ 673
Heo JH / 2009 / White matter hyperintensities and cognitive dysfunction in Alzheimer disease / J Geriatr Psychiatry Neurol 22 : 207 ~ 212
Heo JH / 2010 / Trend in treatment of dementia by benefit cost status based on Health Insurance Review & Assessment Service (HIRA)’s data from 2003 to 2007 / Dement Neur
Heo JH / 2012 / Validation of the Korean Addenbrooke’s Cognitive Examination for Diagnosing Alzheimer’s Dementia and Mild Cognitive Impairment in the Korean Elderly / Appl
Heiserman J / 1992 / Intracranial vascular stenosis and occlusion: evaluation with three-dimentional time-of-flight MR angiography / Radiology 185 : 667 ~ 673
Heo JH / 2009 / White matter hyperintensities and cognitive dysfunction in Alzheimer disease / J Geriatr Psychiatry Neurol 22 : 207 ~ 212
Heo JH / 2010 / Trend in treatment of dementia by benefit cost status based on Health Insurance Review & Assessment Service (HIRA)’s data from 2003 to 2007 / Dement Neur
Heo JH / 2012 / Validation of the Korean Addenbrooke’s Cognitive Examination for Diagnosing Alzheimer’s Dementia and Mild Cognitive Impairment in the Korean Elderly / Appl
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