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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 소화기인터벤션의학회 International Journal of Gastrointestinal Intervention International Journal of Gastrointestinal Intervention 제7권 제3호
- 발행연도
- 2018.1
- 수록면
- 167 - 171 (5page)
이용수
초록· 키워드
오류제보하기
Background: To evaluate the safety and efficacy of transjugular intrahepatic portosystemic shunt (TIPS) creation for the management of portal hypertension in patients with hepatocellular carcinoma (HCC). Methods: A literature search of the MEDLINE/PubMed and Embase databases was conducted. All articles reporting the outcomes of TIPS creation for variceal bleeding and refractory ascites and hepatic hydrothorax in patients with HCC were included. Exclusion criteria were non-English language, sample size < 5, data not extractable, and data reported in another article. Results: A total of 280 patients (mean age, 48–58; male gender, 66%) from five articles were included. TIPS creation was performed for variceal bleeding in 79% and refractory ascites and/or hepatic hydrothorax in 26% of patients. Technical and clinical success was achieved in 99% and 64% of patients, respectively. Clinical failure occurred in 36% of patients due to rebleeding or recurrent bleeding (n = 77) or no resolution or improvement of refractory ascites and hepatic hydrothorax (n = 24). One percent of patient had major complications, including accelerated liver failure (n = 1) and multi-organ failure resulting from hemorrhagic shock (n = 1), all of which resulted in early (i.e., within 30 days) death. Hepatic encephalopathy occurred in 40% of patients after TIPS creation. Lung metastasis was found 1% of patient 5 months (n = 1) and 72 months (n = 1) after TIPS creation. Conclusion: TIPS creation seems to be safe and effective for the management of portal hypertension in patients with HCC.
목차
등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
de Franchis R / 2015 / Expanding consensus in portal hypertension : report of the baveno vi consensus workshop : stratifying risk and individualizing care for portal hypertension / J Hepatol 63:743~752
European Association for the Study of the Liver / 2010 / EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis / J Hepatol 53:397~417
Boyer TD / 2005 / The role of transjugular intrahepatic portosystemic shunt in the management of portal hypertension / Hepatology 41:386~400
Fattovich G / 2004 / Hepatocellular carcinoma in cirrhosis: incidence and risk factors / Gastroenterology 127(5 Suppl 1):S35~S50
Sakaguchi H / 1995 / Combined transjugular intrahepatic portosystemic shunt and segmental lipiodol hepatic artery embolization for the treatment of esophagogastric varices and hepatocellular carcinoma in patients with cirrhosis : preliminary report / Cardiovasc Intervent Radiol 18:9~15
European Association for the Study of the Liver / 2010 / EASL clinical practice guidelines on the management of ascites, spontaneous bacterial peritonitis, and hepatorenal syndrome in cirrhosis / J Hepatol 53:397~417
Boyer TD / 2005 / The role of transjugular intrahepatic portosystemic shunt in the management of portal hypertension / Hepatology 41:386~400
Fattovich G / 2004 / Hepatocellular carcinoma in cirrhosis: incidence and risk factors / Gastroenterology 127(5 Suppl 1):S35~S50
Sakaguchi H / 1995 / Combined transjugular intrahepatic portosystemic shunt and segmental lipiodol hepatic artery embolization for the treatment of esophagogastric varices and hepatocellular carcinoma in patients with cirrhosis : preliminary report / Cardiovasc Intervent Radiol 18:9~15
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