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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 24 - 29 (6page)
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초록· 키워드
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Magnesium alloys are considered as potential biomedical materials due to their mechanical properties, which approximate cortical bone, as well as their biocompatibility. Thermal oxidation is one surface modification method used to increase the corrosion resistance of biomaterial surfaces. Thus, the aim of this study is to assess physical and biological differences of Mg-Ca-Mn alloy depending on oxidation heat treatment methods. The sample were divided into 3 groups: Group II: pure magnesium as a control group; Group II: untreated Mg-Ca-Mn alloy; Group III: Mg-Ca-Mn alloy treated at 500oC for 2 hours. Scanning electron microscope assessment, immersion test, roughness test, and MTT assay were used to evaluate surface characteristics and physical and biologic properties of each sample. Oxide-treated Mg-Ca-Mn alloy treated thermally (Group III) showed an oxidized layer and precipitate with granular structure on the surface. During the immersion test, no significant difference was shown in pH values between the groups. The roughness measurements in Group I and Group III were significantly higher than the value in Group II, while there was no meaningful difference between Group I and Group III. The cell viability of Group III was higher than that of Group II, and statistically significant differences were observed on the third and fifth days. Also, significant differences were confirmed in Group III on the third and fifth days.
Consequently, oxidation heat treatment, among various methods of surface treatment, can be considered as one method to improve properties in biocompatible materials by creating an oxidation layer on Mg-Ca-Mn alloys.
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참고문헌 (20)
참고문헌 신청
Song G / 2007 / Control of biodegradation of biocompatable magnesium alloys / Corros Sci 49:1696~1701
Zhou P / 2012 / Phase stability, mechanical property, and electronic structure of an Mg-Ca system / J Mech Behav Biomed 8:154~164
El-Rahman SS / 2003 / Neuropathology of aluminum toxicity in rats(glutamate and GABA impairment) / Pharmacol Res 47:189~194
Hirano S / 1996 / Exposure, metabolism, and toxicity of rare earths and related compounds / Environ Health Perspect 104(Suppl 1):85~95
Kirkland NT / 2010 / In-vitro dissolution of magnesium-calcium binary alloys : clarifying the unique role of calcium additions in bioresorbable magnesium implant alloys / J Biomed Mater Res B Appl Biomater 95:91~100
Zhou P / 2012 / Phase stability, mechanical property, and electronic structure of an Mg-Ca system / J Mech Behav Biomed 8:154~164
El-Rahman SS / 2003 / Neuropathology of aluminum toxicity in rats(glutamate and GABA impairment) / Pharmacol Res 47:189~194
Hirano S / 1996 / Exposure, metabolism, and toxicity of rare earths and related compounds / Environ Health Perspect 104(Suppl 1):85~95
Kirkland NT / 2010 / In-vitro dissolution of magnesium-calcium binary alloys : clarifying the unique role of calcium additions in bioresorbable magnesium implant alloys / J Biomed Mater Res B Appl Biomater 95:91~100
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