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논문 기본 정보

자료유형
학술저널
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조선대학교 치의학연구원 Oral Biology Research Oral Biology Research 제38권 제1호
발행연도
2014.1
수록면
9 - 16 (8page)

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Purpose: The purpose of the study was to evaluate the bone healing capacity of a xenogenous tooth bone graft material with PDRN (polydeoxyribonucleotide) in a bone defect surrounding an implant in a beagle dog. We compared bone healing capacity between a xenogenic bone graft material (BioOss; Geistlich Pharma AG, Wolhausen, Switzerland) and xenogenous tooth bone graft material. Materials and Methods: The immediate implant placement was done on the 2nd and 3rd premolar extracted sites on both maxilla in six beagle dogs. Artificial bone defects (four in each dog) were made with a length of 5 mm and width of 5 mm. Bone grafts were performed as follows: the xenogenous tooth bone graft material only in group 1; xenogenous tooth bone graft material mixed with PDRN in group 2; xenogenous bone graft material only in group 3; and xenogenous bone graft material mixed with PDRN in group 4. Sacrifices were performed 2, 4, 8 weeks after the experiment. Bone volume ratio around the implant was evaluated through micro-computed tomography. Results: Bone volume ratio around the implant threads increased gradually over time. Groups 2 and 4 showed higher bone volume ratios than groups 1 and 3. Conclusion: Within the limitations of the study, we conclude that application of a bone graft material mixed with PDRN might promote the bone healing process.

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