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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 36 - 44 (9page)
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초록· 키워드
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Objectives: The present study was performed to evaluate the association between serum ferritin concentrations and bone mineral density (BMD) in a representative Korean general population.
Methods: This was a cross-sectional study based on data obtained in the Korean National Health and Nutrition Examination Survey (2008~2010). The present cross-sectional analysis was restricted to participants ≥20 years of age who completed the health examination survey and BMD measurement (n=15,538).
Results: In multiple linear regression analysis of log2-transformed serum ferritin as a continuous variable on BMD, the differences in BMD levels associated with doubling of serum ferritin were -0.0022~-0.0057 in a large representative sample of South Korean women, but not in men. In this large representative sample of South Korean women, elevated serum ferritin level was consistently associated with the prevalence of low bone mass for chronological age. However, there were no significant associations of ferritin level and low bone mass in men.
Conclusion: An association of elevated ferritin level with lower BMD level was observed in the general female population. Thus, our results have substantial public health implications.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Akhlaghpoor S / 2012 / Quantitative T2* magnetic resonance imaging for evaluation of iron deposition in the brain of β-thalassemia patients / Clin Neuroradiol 22 : 211 ~ 21
Chatterjee R / 2011 / Use of hormone replacement therapy for correction of high turnover bone disease in hypogonadal β-Thalassemia major patients presenting with osteoporos
Crichton RR / 2002 / Molecular and cellular mechanisms of iron homeostasis and toxicity in mammalian cells / J Inorg Biochem 91 : 9 ~ 18
Guggenbuhl P / 2005 / Bone mineral density in men with genetic hemochromatosis and HFE gene mutation / Osteoporos Int 16 : 1809 ~ 1814
Ishii KA / 2009 / Coordination of PGC-1beta and iron uptake in mitochondrial biogenesis and osteoclast activation / Nat Med 15 : 259 ~ 266
Chatterjee R / 2011 / Use of hormone replacement therapy for correction of high turnover bone disease in hypogonadal β-Thalassemia major patients presenting with osteoporos
Crichton RR / 2002 / Molecular and cellular mechanisms of iron homeostasis and toxicity in mammalian cells / J Inorg Biochem 91 : 9 ~ 18
Guggenbuhl P / 2005 / Bone mineral density in men with genetic hemochromatosis and HFE gene mutation / Osteoporos Int 16 : 1809 ~ 1814
Ishii KA / 2009 / Coordination of PGC-1beta and iron uptake in mitochondrial biogenesis and osteoclast activation / Nat Med 15 : 259 ~ 266
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