지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 31 - 35 (5page)
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Purpose: To analyze serum markers in proximal femur fracture patients, which are known to be accompanied with osteophorosis or metabolic diseases, and consider it as predictive factor and to study how it affects on the fracture form.
Materials and Methods: Vit. D3 known as serum marker of Vit. D, 25(OH)D, and 1,25(OH)2D of 152 patients from April, 2013 to March, 2014 who visited our hospital and diagnosed as proximal femur fracture(Femur neck fracture 73, Intertrochanteric fracture 79) were analyzed. Also, serum calcium level corrected by serum protein, phosphate, creatinine, alkaline phosphatase, estradiol, IGF-1, and PTH were compared and analyzed.
Results: Femur neck fracture group showed significantly low value of D3, 25(OH)D, and 1,25(OH)2D (P-value<0.05) as the values were 37.72±7.21 pg/mL, 27.05±8.43 ng/mL, 25.05±6.78 pg/mL in femur neck fracture group, and 40.36±6.97 pg/mL, 29.54±9.12 ng/mL, 28.87±7.43 pg/mL in intertrochanteric fracture group respectively. The number of patients who were diagnosed as hypovitaminosis D. due to serum 25(OH)D value lower than 30ng/ml were significantly high in femur neck fracture group as the numbers were 56 in femur neck fracture, and 44 in intertrochanteric fracture. Serum calcium level corrected by serum protein, phosphate, creatinine, alkaline phosphatase, estradiol, IGF-1 and PTH level showed no significant difference between two groups.
Conclusion: Serum 25(OH)D level was decreased in proximal femur fracture patiens, and was lower as the patient was older and BMD was lower. Therefore it is thought that proximal femur fracture is affected by vitamin D metabolism.
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등록된 정보가 없습니다.
참고문헌 (17)
참고문헌 신청
Barrett-Connor E / 1998 / Gender differences in insulin-like growth factor and bone mineral density association in old age: the Rancho Bernardo Study / J Bone Miner Res 13 :
Bennett AE / 1984 / Insulin-like growth factors I and II: aging and bone density in women / J Clin Endocrinol Metab 59 : 701 ~ 704
Bogunovic L / 2010 / Hypovitaminosis D in Patients Scheduled to Undergo Orthopaedic Surgery: A Single-Center Analysis / J Bone Joint Surg Am 92 : 2300 ~ 2304
Boonen S / 2004 / Functional outcome and quality of life following hip fracture in elderly women: a prospective controlled study / Osteoporosis Int 15 : 87 ~ 94
Cummings SR / 1990 / The future of hip fractures in the United States. Numbers, costs and potential effects of postmenopausal estrogen / Clin Orthop Relat Res 252 : 163 ~ 166
Bennett AE / 1984 / Insulin-like growth factors I and II: aging and bone density in women / J Clin Endocrinol Metab 59 : 701 ~ 704
Bogunovic L / 2010 / Hypovitaminosis D in Patients Scheduled to Undergo Orthopaedic Surgery: A Single-Center Analysis / J Bone Joint Surg Am 92 : 2300 ~ 2304
Boonen S / 2004 / Functional outcome and quality of life following hip fracture in elderly women: a prospective controlled study / Osteoporosis Int 15 : 87 ~ 94
Cummings SR / 1990 / The future of hip fractures in the United States. Numbers, costs and potential effects of postmenopausal estrogen / Clin Orthop Relat Res 252 : 163 ~ 166
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