지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 367 - 374 (8page)
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초록· 키워드
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Invasive Candida infections (ICI) have become the third most common cause of late-onset infection among extremely preterm infants in the neonatal intensive care unit. Candida colonization of the skin and gastrointestinal tract is an important first step in the pathogenesis of invasive disease. Factors such as exposure to broad spectrum antimicrobials, especially third generation cephalosporin, parenteral nutrition including lipid emulsion, central venous catheter, and abdominal surgery increase the risk of invasive infection. A definite diagnosis of ICI requires isolation the organism from blood or other sterile body fluid. Thrombocytopenia is very common in neonatal candidiasis, but it is also often seen in babies with bacteremia. Candida is capable of invading all vital organs and following candidemia, therefore a thorough evaluation to rule out end organ dissemination is important. Amphotericin-B is the drug of choice for treating ICI. Antifungal susceptibility test is increasingly used to manage ICI, especially in situations refractory to initial antifugal therapy. Invasive candidiasis among extremely preterm infants is associated with chronic lung disease,severe retinopathy of prematurity, and neurodevelopmental impairment at infancy.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
Baley JE / 1986 / Fungal colonization in the very low birth weight infant / Pediatrics 78 : 225 ~ 232
Benjamin DK Jr / 2003 / Neonatal candidemia and end-organ damage: a critical appraisal of the literature using meta-analytic techniques / Pediatrics 112 : 634 ~ 640
Benjamin DK Jr / 2006 / Neonatal candidiasis among extremely low birth weight infants: risk factors, mortality rates, and neurodevelopmental outcomes at 18 to 22 months / Ped
Borghesi A / 2008 / Strategies for the prevention of hospital- acquired infections in the neonatal intensive care unit / J Hosp Infect 68 : 293 ~ 300
Chapman RL / 2000 / Persistently positive cultures and outcome in invasive neonatal candidiasis / Pediatr Infect Dis J 19 : 822 ~ 827
Benjamin DK Jr / 2003 / Neonatal candidemia and end-organ damage: a critical appraisal of the literature using meta-analytic techniques / Pediatrics 112 : 634 ~ 640
Benjamin DK Jr / 2006 / Neonatal candidiasis among extremely low birth weight infants: risk factors, mortality rates, and neurodevelopmental outcomes at 18 to 22 months / Ped
Borghesi A / 2008 / Strategies for the prevention of hospital- acquired infections in the neonatal intensive care unit / J Hosp Infect 68 : 293 ~ 300
Chapman RL / 2000 / Persistently positive cultures and outcome in invasive neonatal candidiasis / Pediatr Infect Dis J 19 : 822 ~ 827
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