지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 158 - 165 (8page)
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초록· 키워드
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Purpose: To compare respiratory and clinical outcomes between the currently used strategy of Intubation, Surfactant, Extubation (InSurE) and nasal continuous positive airway pressure (NCPAP) and the alternative strategy of InSurE and nasal intermittent positive pressure ventilation (NIPPV) for the initial treatment of respiratory distress syndrome (RDS) in preterm newborns ≤32 weeks.
Methods: Twenty-six comparable preterm infants with RDS were included in the study; 13 were randomized to NCPAP and 13 to NIPPV. In both groups, the InSurE procedure consisted of intubation, surfactant instillation and 2 h positive pressure ventilation followed by extubation, after which spontaneously breathing newborns were placed on NCPAP or NIPPV.
Results: There were no differences in demographic characteristics or cardiorespiratory status among preterm infants enrolled in the study. The reinutation rate was lower among the infants treated with NIPPV than among those on NCPAP (8% vs. 46%, P<0.05) and the rate of aminophylline use between 4 and 7 days of age of was lower in the NIPPV group compared to the NCPAP group (8% vs. 30%, P<0.05). In addition, “InSurE with NIPPV” significantly reduced the overall duration of endotracheal ventilation and shortened the time to first feed compared to “InSurE with NCPAP”.
Conclusion: “InSurE with NIPPV” displayed therapeutic benefits as the initial treatment of preterm RDS when compared with the currently used ventilator strategy, “InSurE with NCPAP” by preventing re-intubation and shortening the duration of endotracheal ventilation.
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참고문헌 (22)
참고문헌 신청
/ 1984 / The Committee for the Classification of Retinopathy of Prematurity. An international classification of retinopathy of prematurity / Arch Ophthalmol 102 : 1130 ~ 113
Barrington K / 2001 / Randomized trial of nasal synchronized intermittent mandatory ventilation compared with continuous positive airway pressure after extubation of very lo
Bell MJ / 1978 / Neonatal necrotizing enterocolitis: therapeutic decisions based on clinical staging / Ann Surg 187 : 1 ~ 7
De Klerk AM / 2001 / Nasal continuous positive airway pressure and outcomes of preterm infants / J Pediatr Child Health 37 : 161 ~ 167
De Paoli AG / 2003 / Nasal continuous positive airway pressure versus nasal intermittent positive ventilation for preterm neonates: a syst
Barrington K / 2001 / Randomized trial of nasal synchronized intermittent mandatory ventilation compared with continuous positive airway pressure after extubation of very lo
Bell MJ / 1978 / Neonatal necrotizing enterocolitis: therapeutic decisions based on clinical staging / Ann Surg 187 : 1 ~ 7
De Klerk AM / 2001 / Nasal continuous positive airway pressure and outcomes of preterm infants / J Pediatr Child Health 37 : 161 ~ 167
De Paoli AG / 2003 / Nasal continuous positive airway pressure versus nasal intermittent positive ventilation for preterm neonates: a syst
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