A Case of Long-Term Complete Remission of Advanced Gastric Adenocarcinoma with Liver Metastasis

임창범; 이정애; 공수정; 강동욱; 양희범; 한현영; 김내유

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자료유형: 학술저널

저자정보: 임창범 이정애 공수정 강동욱 양희범 한현영 김내유

저널정보: 대한위암학회 Journal of Gastric Cancer Journal of Gastric Cancer 제16권 제2호

발행연도: 2016.1

수록면: 115 - 119 (5page)

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We report the case of a patient with gastric adenocarcinoma with multiple liver metastases. This patient showed complete remissionfor more than 68 months after S-1/cisplatin combination chemotherapy and radical total gastrectomy. The patient, a 63-year-old man,presented with dyspepsia and difficulty in swallowing. Endoscopic findings showed a huge ulcero-infiltrative mass at the lesser curvatureof the mid-body, extending to the distal esophagus. Biopsy revealed a poorly differentiated tubular adenocarcinoma. An abdominal computedtomography scan demonstrated multiple hepatic metastases. S-1/cisplatin combination chemotherapy was initiated, and followingcompletion of six cycles of chemotherapy, the gastric masses and hepatic metastatic lesions had disappeared on abdominal computedtomography. Radical total gastrectomy and D2 lymphadenectomy combined with splenectomy were performed. The patient underwentthree cycles of S-1/cisplatin combination chemotherapy followed by tegafur-uracil therapy for 1 year. He remained in complete remissionfor more than 68 months after surgery.

#Gastric cancer #Liver metastasis #Gastrectomy #S-1 #Cisplatin #Cisplatin

참고문헌 (12)

참고문헌 신청

Siegel RL / 2015 / Cancer statistics, 2015 / CA Cancer J Clin 65:5~29

Glimelius B / 1997 / Randomized comparison between chemotherapy plus best supportive care with best supportive care in advanced gastric cancer / Ann Oncol 8:163~168

Rosati G / 2009 / New perspectives in the treatment of advanced or metastatic gastric cancer / World J Gastroenterol 15:2689~2692

Koizumi W / 2008 / S-1 plus cisplatin versus S-1 alone for first-line treatment of advanced gastric cancer(SPIRITS trial) : a phase III trial / Lancet Oncol 9:215~221

Iwahashi M / 2001 / Complete response of highly advanced gastric cancer with peritoneal dissemination after new combined chemotherapy of S-1 and low-dose cisplatin : report of a case / Oncology 61:16~22

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