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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2015.1
- 수록면
- 41 - 48 (8page)
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Purpose: We investigated potential difference in the clinical features of hospitalized female acute pyelonephritis (APN) patients with and without diabetes mellitus (DM). The additional purpose of the study was to determine whether HbA1c has a role in predicting clinical outcome in terms of morbidity compared with those considered to have normal glycemic control in female APN patients with DM.Materials and Methods: Among the female patients who received inpatients care due to APN from January 2011 to December 2013, 282 patients (86 with DM and 196 without DM) were selected and their medical records were analyzed. Laboratory results (white blood cell, blood urea nitrogen, serum creatinine, fasting plasma glucose, HbA1c) were dichotomized. Primary outcomes for comparison between the groups of patients with or without DM were early clinical response rate and length of in-hospital stay. Subgroup analysis was also performed in DM patients according to HbA1c status (<6.5%, ≥6.5%).Results: In multivariate logistic regression analysis, DM was not found to show independent association with poor early clinical response or longer hospital stay. HbA1c was the common risk factor of poor early clinical response (odds ratio [OR] 4.88, 95% confidence interval [CI] 1.61-14.8) and longer hospital stay (OR 4.20 95% CI 1.52-11.60) in APN patients with DM.Conclusions: Strict glucose control may be more important prognostic factor than presence or absence of DM in APN patients. As a marker of prolonged hospitalization and poor early clinical response, HbA1c can complement the present clinical and laboratory parameters used as guide in the proper treatment of DM patients with APN.
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참고문헌 (27)
참고문헌 신청
[학술지(정기간
Bennett CM / 2007 / HbA(1c) as a screening tool for detection of Type 2 diabetes: a systematic review / Diabet Med 24 : 333 ~ 343
Brown P / 2005 / Acute pyelonephritis among adults: cost of illness and considerations for the economic evaluation of therapy / Pharmacoeconomics 23 : 1123 ~ 1142
Efstathiou SP / 2003 / Acute pyelonephritis in adults: prediction of mortality and failure of treatment / Arch Intern Med 163 : 1206 ~ 1212
Gornik I / 2007 / HbA1c is outcome predictor in diabetic patients with sepsis / Diabetes Res Clin Pract 77 : 120 ~ 125
Bennett CM / 2007 / HbA(1c) as a screening tool for detection of Type 2 diabetes: a systematic review / Diabet Med 24 : 333 ~ 343
Brown P / 2005 / Acute pyelonephritis among adults: cost of illness and considerations for the economic evaluation of therapy / Pharmacoeconomics 23 : 1123 ~ 1142
Efstathiou SP / 2003 / Acute pyelonephritis in adults: prediction of mortality and failure of treatment / Arch Intern Med 163 : 1206 ~ 1212
Gornik I / 2007 / HbA1c is outcome predictor in diabetic patients with sepsis / Diabetes Res Clin Pract 77 : 120 ~ 125
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