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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2014.1
- 수록면
- 9 - 13 (5page)
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Urinary tract infections (UTI) are one of the most common infections affecting women. In a recent study of college women with their first UTI, 27% experienced at least one culture-confirmed recurrence within the six months following the initial infection and 2.7% had a second recurrence during this time period. Women with recurrent UTI have an increased susceptibility to vaginal colonization with uropathogens due to a greater propensity for them to adhere to their epithelial cells. Risk factors include frequent sexual intercourse, spermicide use, first UTI at an early age, and maternal history of UTI. Effectiveness of continuous or post-coital prophylaxis with low-dose antimicrobials or intermittent self-treatment with antimicrobials in management of recurrent uncomplicated UTIs in women has been demonstrated. However, antibiotics are the main driving force in development of antibiotic resistance and can lead to resistance of not only the causative microorganisms, but also the commensal flora. The increasing prevalence of Escherichia coli isolates (the most prevalent uropathogen) that are resistant to antimicrobial agents has stimulated interest in non-antibiotic methods for prevention of UTIs. We discuss the overall use of non-antibiotic methods for prevention of recurrent UTI, including the use of immunostimulant OM-89, a vaginal vaccine or estrogen, lactobacilli prophylaxis, and cranberry.
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참고문헌 (23)
참고문헌 신청
Anderson GL / 2004 / Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women's Health Initiative randomized controlled trial / JAMA 291 :
Backhed F / 2001 / Induction of innate immune responses by Escherichia coli and purified lipopolysaccharide correlate with organ-and cell-specific expression of Toll-like rec
Baerheim A / 1994 / Vaginal application of lactobacilli in the prophylaxis of recurrent lower urinary tract infection in women / Scand J Prim Health Care 12 : 239 ~ 243
Bauer HW / 2005 / A long-term, multicenter, double-blind study of an Escherichia coli extract (OM-89) in female patients with recurrent urinary tract infections / Eur Urol 4
Beerepoot MA / 2012 / Lactobacilli vs antibiotics to prevent urinary tract infections : a randomized, double-blind, noninferiority trial in postmenopausal women / Arch Intern
Backhed F / 2001 / Induction of innate immune responses by Escherichia coli and purified lipopolysaccharide correlate with organ-and cell-specific expression of Toll-like rec
Baerheim A / 1994 / Vaginal application of lactobacilli in the prophylaxis of recurrent lower urinary tract infection in women / Scand J Prim Health Care 12 : 239 ~ 243
Bauer HW / 2005 / A long-term, multicenter, double-blind study of an Escherichia coli extract (OM-89) in female patients with recurrent urinary tract infections / Eur Urol 4
Beerepoot MA / 2012 / Lactobacilli vs antibiotics to prevent urinary tract infections : a randomized, double-blind, noninferiority trial in postmenopausal women / Arch Intern
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