Clinical Experience of Isolated Metachronous Adrenal Gland Metastases from Solid Primary Carcinomas

조민재; 조재원; 이유미; 성태연; 윤종호; 정기욱; 홍석준

추천

검색

자료유형: 학술저널

저자정보: 조민재 조재원 이유미 성태연 윤종호 정기욱 홍석준

저널정보: 대한갑상선-내분비외과학회 The Journal of Endocrine Surgery The Journal of Endocrine Surgery 제17권 제2호

발행연도: 2017.1

수록면: 73 - 79 (7page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

Purpose: Owing to the development of improved techniques, the use of adrenal gland surgery for the treatment of metachronous metastatic adrenal tumors originating from primary carcinomas has increased. Here, we have analyzed the postoperative outcomes of patients who received surgical treatment for isolated metastatic adrenal gland originated from solid primary carcinomas. Methods: Patients who underwent metastatic adrenalectomy after treatment of the primary carcinoma at the Asan Medical Center from 2000 to 2010 were included. Clinicopathological parameters were analyzed to determine the prognostic outcomes. Results: Our study cohort consisted of 21 patients with hepatocellular carcinoma (n=10), lung carcinoma (n=8), and colorectal carcinoma (n=3). The mean age was 54.6 years old. The mean overall survival (OS) duration was 78.5 months. Disease-specific recurrence-free survival (RFS) after metastatic adrenalectomy was significantly longer when the interval between primary carcinoma treatment and metachronous metastasis to the adrenal glands was ≥16 months (P=0.043). There was no significant difference in disease-specific RFS between patients who underwent open adrenalectomy (OA) vs. laparoscopic adrenalectomy (LA) (P=0.063). Conclusion: Surgical treatment should be recommended for isolated metachronous adrenal gland metastases when the interval between primary carcinoma treatment and metastasis is ≥16 months to achieve better disease-specific RFS. LA was not inferior to OA.

#Adrenal glands #Neoplasm metastasis #Neoplasms #second primary #Adrenalectomy #Survival

참고문헌 (18)

참고문헌 신청

Tomasini P / 2017 / Adrenal surgery for oligometastatic tumors improves survival in selected cases / J Visc Surg 154:87~91

Marangos IP / 2009 / Should we use laparoscopic adrenalectomy for metastases? Scandinavian multicenter study / J Surg Oncol 100:43~47

Solaini L / 2015 / Adrenalectomy for metastasis: long-term results and predictors of survival / Endocrine 50:187~192

Kim SH / 1998 / The role of surgery in the treatment of clinically isolated adrenal metastasis / Cancer 82:389~394

Ferlay J / 2015 / Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012 / Int J Cancer 136:E359~E386

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!