지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2011.1
- 수록면
- 139 - 145 (7page)
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Iodine-131 (I-131) has been used in the therapy of well-differentiated thyroid cancer for over 60 years and has been an important component in the management of well-differentiated thyroid cancer. Differentiated thyroid carcinoma (DTC) is one of the most curable cancers, associated with a 10-year survival rate of 80∼95%. Total (or near-total) thyroidectomy followed by radioiodine ablation is considered to be the ideal treatment for the high risk tumors. The selective use of radioactive iodine on the basis of clinicopathologic features that define the risk of recurrence and disease specific mortality is generally recommended in many kinds of international or institutional guidelines. However, recurrence in the thyroid bed or cervical lymph nodes develops in 5∼20% of patients with DTC and some patients develop distant metastatic disease decreasing the 10- year survival of patients by 50%. Unfortunately, many of these patients ultimately die from advanced disease and other therapeutic approaches are needed. The goals of therapy for those patients should be to improve survival, relieve symptoms, and decrease the morbidity of disease progression and limit the morbidity associated with therapy. Safe practice of radioiodine treatment should be balanced with the benefit and the risk. This review will address the results of the radioiodine treatments in patients with the advanced thyroid cancer with the recent clinical trials. (Korean J Endocrine Surg 2011;11:139-145)
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참고문헌 (23)
참고문헌 신청
Alzahrani AS / 2005 / Long-term course and predictive factors of elevated serum thyroglobulin and negative diagnostic radioiodine whole body scan in differentiated thyroid c
Chao M / 2010 / Management of differentiated thyroid cancer with rising thyroglobulin and negative diagnostic radioiodine whole body scan / Clin Oncol (R Coll Radiol) 22 : 4
Chiu AC / 1997 / Prognosis and treatment of brain metastases in thyroid carcinoma / J Clin Endocrinol Metab 82 : 3637 ~ 3642
Gutierrez Cardo AL / 2007 / Patients treated for differentiated thyroid cancer with negative 131I whole-body scans and elevated thyroglobulin levels: a possi
Haigh PI / 2005 / Extent of thyroidectomy is not a major determinant of survival in low- or high-risk papillary thyroid cancer / Ann Surg Oncol 12 : 81 ~ 89
Chao M / 2010 / Management of differentiated thyroid cancer with rising thyroglobulin and negative diagnostic radioiodine whole body scan / Clin Oncol (R Coll Radiol) 22 : 4
Chiu AC / 1997 / Prognosis and treatment of brain metastases in thyroid carcinoma / J Clin Endocrinol Metab 82 : 3637 ~ 3642
Gutierrez Cardo AL / 2007 / Patients treated for differentiated thyroid cancer with negative 131I whole-body scans and elevated thyroglobulin levels: a possi
Haigh PI / 2005 / Extent of thyroidectomy is not a major determinant of survival in low- or high-risk papillary thyroid cancer / Ann Surg Oncol 12 : 81 ~ 89
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