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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Introduction: Bone mineral density (BMD) is an important index in diagnosis of osteo-porosis and other metabolic bone diseases, prediction of fractures, and monitoringtreatment. This study was to find a more feasible technique for prediction of osteoporot-ic fracture between dual energy X-ray absorptiometry (DXA) and quantitative computedtomography (QCT) and to reveal the actual change of bone strength when BMD waschanged. Methods: Ten of these 20 specimens were used as the demineralized groupand the other 10 as the control. Each specimen was immersed in HCl solution at for aperiod of at least 10 minutes, up to 100 minutes, at an interval of 10 minutes for differ-ent levels of demineralization. BMD was measured using DXA and QCT. Uniaxial com-pression tests were conducted to mea sure biomechanical parameters. Pearson correla-tion analysis was used respectively be tween BMD and biomechanical parameters andbetween DXA and QCT. Results: Elastic modulus (r=0.87) and yield stress (r=0.84)showed a statistically significant correlation with DXA BMD. Through correlation analysiswith QCT BMD and elastic modulus, correlation coef ficient showed hemi-vertebra(r=0.80) and trabecular (r=0.68). In yield stress, there was a statistically significant cor-relation in hemi-vertebra (r=0.87) and trabecular bone (r=0.84). Conclusion: DXA is acurrent standard technique not only for diagnosis of osteoporosis but also for predictionof fracture risk compared to QCT. Actual decrease of bone strength was much greaterthan that of BMD by both DXA and QCT.
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참고문헌 (23)
참고문헌 신청
Actis AB / 2004 / Influence of different sterilization procedures and partial demineralization of screws made of bone on their mechanical properties / J Biomater Appl 18 : 1
Bayraktar HH / 2004 / Comparison of the elastic and yield properties of human femoral trabecular and cortical bone tissue / J Biomech. 37 : 27 ~ 35
Bergot C / 2001 / A comparison of spinal quantitative computed tomography with dual energy X-ray absorptiometry in European women with vertebral and nonvertebral fractures /
Black DM / 2008 / Proximal femoral structure and the prediction of hip fracture in men : a large prospective study using QCT / J Bone Miner Res. 23 : 1326 ~ 1333
Block JE / 1989 / Models of spinal trabecular bone loss as determined by quantitative computed tomography / J Bone Miner Res 4 : 249 ~ 257
Bayraktar HH / 2004 / Comparison of the elastic and yield properties of human femoral trabecular and cortical bone tissue / J Biomech. 37 : 27 ~ 35
Bergot C / 2001 / A comparison of spinal quantitative computed tomography with dual energy X-ray absorptiometry in European women with vertebral and nonvertebral fractures /
Black DM / 2008 / Proximal femoral structure and the prediction of hip fracture in men : a large prospective study using QCT / J Bone Miner Res. 23 : 1326 ~ 1333
Block JE / 1989 / Models of spinal trabecular bone loss as determined by quantitative computed tomography / J Bone Miner Res 4 : 249 ~ 257
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